Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.73 |
| ▸ | CHKA | P35790 | 1/20 | 0.73 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HBB | P68871 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8781228 | 0.89 | CHRM5 (0.57) | CHRM5CHKAMAPTSMN1; SMN2ALOX15 | |
| SCHEMBL189 | 0.85 | — | — | |
| SCHEMBL8664726 | 0.85 | CHRM5 (1.00) | CHRM5CHKAMAPTSMN1; SMN2ALOX15 | |
| SCHEMBL9135564 | 0.84 | CHRM5 (0.70) | CHRM5CHKAMAPTSMN1; SMN2ALOX15 | |
| Alcohol SCHEMBL25433719 | 0.84 | CHRM5 (0.76) | CHRM5CHKAMAPTSMN1; SMN2ALOX15 | |
| Butane SCHEMBL29281770 | 0.84 | CHRM5 (0.76) | CHRM5CHKAMAPTSMN1; SMN2ALOX15 | |
| Hydrochloric Acid SCHEMBL9013636 | 0.83 | CHRM5 (0.94) | CHRM5CHKAMAPTSMN1; SMN2ALOX15 | |
| SCHEMBL2277093 | 0.83 | CHRM5 (0.94) | CHRM5CHKAMAPTSMN1; SMN2ALOX15 | |
| SCHEMBL4405649 | 0.83 | CHRM5 (0.94) | CHRM5CHKAMAPTSMN1; SMN2ALOX15 | |
| Bromide SCHEMBL393564 | 0.83 | CHRM5 (0.94) | CHRM5CHKAMAPTSMN1; SMN2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112370537-A | Double-targeting magnetic fluorescent nano-microsphere, preparation method thereof and application thereof in circulating tumor cells of liver cancer | 大连理工大学 | 2021-02-19 | — | — | CN | claimed |
| CN-108794705-A | A kind of preparation method and application of modified carboxyl styrene-butadiene latex | 江南大学 | 2018-11-13 | — | — | CN | claimed |
| CN-112370537-B | Double-targeting magnetic fluorescent nanoparticle, preparation method thereof and application thereof in liver cancer circulating tumor cells | 大连理工大学 | 2023-08-11 | — | — | CN | disclosed |
| CN-112370537-A | Double-targeting magnetic fluorescent nano-microsphere, preparation method thereof and application thereof in circulating tumor cells of liver cancer | 大连理工大学 | 2021-02-19 | — | — | CN | disclosed |
| CN-110352006-A | PICOLINAMIDES AS FUNGICIDES | 美国陶氏益农公司 | 2019-10-18 | — | — | CN | disclosed |
| CN-108794705-A | A kind of preparation method and application of modified carboxyl styrene-butadiene latex | 江南大学 | 2018-11-13 | — | — | CN | disclosed |
| CN-104496901-B | The manufacture method of anthranilamide compound | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2016-05-25 | — | — | CN | disclosed |
| CN-102101839-B | Polycarbonate with improved thermal and mechanical properties and reduced thermal expansion coefficient | BAYER MATERIALSCIENCE AG | 2014-12-24 | — | — | CN | disclosed |
| CN-102227463-A | Copolycarbonates with improved surface hardness | BAYER MATERIALSCIENCE AG | 2011-10-26 | — | — | CN | disclosed |
| CN-102101839-A | Polycarbonate with improved thermal and mechanical properties and reduced thermal expansion coefficient | BAYER MATERIALSCIENCE AG | 2011-06-22 | — | — | CN | disclosed |
| CN-102093685-A | Polycarbonate compositions with improved surface hardness | BAYER MATERIALSCIENCE AG | 2011-06-15 | — | — | CN | disclosed |
| CN-1128790-C | 4-hydroxyquinoline-3-carboxamides and hydrazides as antiviral agents | UPJOHN CO (US) | 2003-11-26 | — | — | CN | disclosed |
| CN-1281439-A | 4-hydroxyquinoline-3-carboxamide and hydrazide compounds as antiviral agents | UPJOHN CO (US) | 2001-01-24 | — | — | CN | disclosed |
| CN-1046736-C | As steroids C17－20Delta of lyase inhibitors16Unsaturated C17Heterocyclic steroids | MERRELL DOW PHARMA (US) | 1999-11-24 | — | — | CN | disclosed |
| CN-1133596-A | 'Delta' 16 unsaturated C17 heterocyclic steroids useful as steroid C17-20 lyase inhibitors | MERRELL DOW PHARMA (US) | 1996-10-16 | — | — | CN | disclosed |
| CN-1028477-C | Microbicide composition containing thiazolyl-5-carboxamide derivatives | CIBA GEIGY AG (CH) | 1995-05-24 | — | — | CN | disclosed |
| CN-1052675-A | Insecticides | CIBA GEIGY AG (CH) | 1991-07-03 | — | — | CN | disclosed |
| EP-0032400-B1 | (3SR, 4RS)-3-((RS)-1-HYDROXYETHYL)- AND -((RS)-1-ACYLOXYETHYL)-2-OXO-4-AZETIDINEACETIC ACID COMPOUNDS AND A PROCESS FOR PREPARING THE SAME | MERCK & CO. INC. (US) | 1984-06-20 | — | — | EP | disclosed |
| US-4287123-A | Synthesis of thienamycin via (3SR, 4RS)-3-((RS)-1-acyloxyethyl)-2-oxo-4-azetidineacetate | MERCK & CO., INC. (US) | 1981-09-01 | — | — | US | disclosed |
| EP-0032400-A1 | (3SR, 4RS)-3-((RS)-1-hydroxyethyl)- and -((RS)-1-acyloxyethyl)-2-oxo-4-azetidineacetic acid compounds and a process for preparing the same | MERCK & CO. INC. (US) | 1981-07-22 | — | — | EP | disclosed |