Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 6/20 | 0.89 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.73 |
| ▸ | GAA | P10253 | 4/20 | 0.73 |
| ▸ | HPGD | P15428 | 4/20 | 0.73 |
| ▸ | GLA | P06280 | 3/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.73 |
| ▸ | CASP1 | P29466 | 2/20 | 0.73 |
| ▸ | CASP7 | P55210 | 2/20 | 0.73 |
| ▸ | TSHR | P16473 | 1/20 | 0.73 |
| ▸ | ERAP1 | Q9NZ08 | 3/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
| ▸ | SRC | P12931 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | NQO1 | P15559 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10795060 | 0.96 | HSD17B3 (0.86) | HSD17B3KDM4EALDH1A1GAAHPGD | |
| SCHEMBL3767036 | 0.94 | HSD17B3 (1.00) | HSD17B3KDM4EALDH1A1GAAHPGD | |
| SCHEMBL10794644 | 0.90 | HSD17B3 (0.72) | HSD17B3KDM4EALDH1A1GAAHPGD | |
| SCHEMBL10789385 | 0.89 | HSD17B3 (0.71) | HSD17B3KDM4EALDH1A1GAAHPGD | |
| Ocimarin SCHEMBL23752453 | 0.88 | HSD17B3 (0.79) | HSD17B3KDM4EALDH1A1GAAHPGD | |
| SCHEMBL3761517 | 0.88 | HSD17B3 (0.78) | HSD17B3KDM4EALDH1A1GAAHPGD | |
| SCHEMBL29725796 | 0.88 | HSD17B3 (0.78) | HSD17B3KDM4EALDH1A1GAAHPGD | |
| SCHEMBL10791187 | 0.86 | HSD17B3 (0.71) | HSD17B3KDM4EALDH1A1GAAHPGD | |
| SCHEMBL10792242 | 0.86 | HSD17B3 (0.71) | HSD17B3KDM4EALDH1A1GAAHPGD | |
| SCHEMBL27921549 | 0.85 | KDM4E (0.85) | HSD17B3KDM4EALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4427680-A | ANTHISTAMINES | BOEHRINGER MANNHEIM GMBH (DE) | 1984-01-24 | — | — | US | disclosed |
| US-4330549-A | Coumarins connected via an oxyalkyl group with a piperidine ring having anti-allergic action | BOEHRINGER MANNHEIM GMBH (DE) | 1982-05-18 | — | — | US | disclosed |
| EP-0013894-B1 | ARYLETHERS, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1982-02-03 | — | — | EP | disclosed |
| EP-0013894-A1 | Arylethers, process for their preparation and medicines containing them | Roche Diagnostics GmbH (DE) | 1980-08-06 | — | — | EP | disclosed |