Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1238087 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL11109527 | 0.80 | POLB (0.32) | POLBSMN1; SMN2L3MBTL1PAOX | |
| SCHEMBL23157016 | 0.77 | — | — | |
| SCHEMBL1525879 | 0.77 | — | — | |
| SCHEMBL5886710 | 0.73 | POLB (0.32) | POLBSMN1; SMN2L3MBTL1PAOX | |
| SCHEMBL10739583 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL29286840 | 0.72 | PAOX (0.33) | POLBSMN1; SMN2L3MBTL1PAOX | |
| SCHEMBL16819051 | 0.71 | POLB (0.31) | POLBSMN1; SMN2L3MBTL1PAOX | |
| SCHEMBL1720452 | 0.71 | — | — | |
| SCHEMBL11424423 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0041233-B1 | SUBSTITUTED PHENOXY-AMINOPROPANOL DERIVATIVES, INTERMEDIATES AND PROCESSES FOR THEIR PRODUCTION, AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-02-15 | — | — | EP | claimed |