Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16168058 | 0.79 | MEN1 (0.56) | MEN1KMT2ACHRM2CHRM4CHRM5 | |
| SCHEMBL9177864 | 0.78 | MEN1 (0.46) | MEN1KMT2ACHRM2CHRM4CHRM5 | |
| SCHEMBL12269652 | 0.78 | MTOR (0.61) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL6512237 | 0.78 | MTOR (0.61) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL12830195 | 0.78 | MTOR (0.61) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL10952708 | 0.76 | CHRM2 (0.46) | MEN1KMT2ACHRM2CHRM4CHRM5 | |
| SCHEMBL13389739 | 0.76 | CHRM2 (0.46) | MEN1KMT2ACHRM2CHRM4CHRM5 | |
| SCHEMBL13379545 | 0.76 | CHRM2 (0.46) | MEN1KMT2ACHRM2CHRM4CHRM5 | |
| SCHEMBL17585009 | 0.74 | GAA (0.46) | MEN1KMT2ACHRM2CHRM4CHRM5 | |
| SCHEMBL16114585 | 0.73 | KDM4E (0.46) | MEN1KMT2AKDM4EALOX5AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0067080-B1 | N-FLUORINATED BENZYL AMIDES AND PROCESS FOR THEIR PREPARATION | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1984-11-21 | — | — | EP | disclosed |
| EP-0067080-A1 | N-fluorinated benzyl amides and process for their preparation | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1982-12-15 | — | — | EP | disclosed |