Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL981112 | 1.00 | TSHR (0.40) | TSHRTHRBLPAR3LPAR2LPAR1 | |
| SCHEMBL983048 | 1.00 | TSHR (0.40) | TSHRTHRBLPAR3LPAR2LPAR1 | |
| SCHEMBL980258 | 1.00 | TSHR (0.40) | TSHRTHRBLPAR3LPAR2LPAR1 | |
| SCHEMBL983036 | 1.00 | TSHR (0.40) | TSHRTHRBLPAR3LPAR2LPAR1 | |
| SCHEMBL352158 | 1.00 | TSHR (0.40) | TSHRTHRBLPAR3LPAR2LPAR1 | |
| SCHEMBL980131 | 1.00 | TSHR (0.40) | TSHRTHRBLPAR3LPAR2LPAR1 | |
| SCHEMBL980849 | 1.00 | TSHR (0.40) | TSHRTHRBLPAR3LPAR2LPAR1 | |
| SCHEMBL981238 | 1.00 | TSHR (0.40) | TSHRTHRBLPAR3LPAR2LPAR1 | |
| SCHEMBL982550 | 1.00 | TSHR (0.40) | TSHRTHRBLPAR3LPAR2LPAR1 | |
| SCHEMBL981134 | 1.00 | TSHR (0.40) | TSHRTHRBLPAR3LPAR2LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2921518-A1 | ORGANOPOLYSILOXANE HAVING AMIDE GROUP, AND COSMETIC MATERIAL CONTAINING SAME | Shin-Etsu Chemical Co., Ltd. (JP) | 2015-09-23 | — | — | EP | disclosed |
| EP-2280040-B1 | Organopolysiloxane having amide group, and cosmetic material containing same | SHINETSU CHEMICAL CO (JP) | 2015-04-15 | — | — | EP | disclosed |
| US-8398964-B2 | Organopolysiloxane having amide group, and cosmetic material containing same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2013-03-19 | — | — | US | disclosed |
| US-20110027213-A1 | ORGANOPOLYSILOXANE HAVING AMIDE GROUP, AND COSMETIC MATERIAL CONTAINING SAME | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2011-02-03 | — | — | US | disclosed |
| EP-2280040-A1 | Organopolysiloxane having amide group, and cosmetic material containing same | Shin-Etsu Chemical Co., Ltd. (JP) | 2011-02-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110027213-A1 | ORGANOPOLYSILOXANE HAVING AMIDE GROUP, AND COSMETIC MATERIAL CONTAINING SAME | HRH3, H1-3, HRH1 | TSHR 384/4885THRB 993/4885LPAR3 383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.