SCHEMBL11097500

SCHEMBL11097500

NCC(=O)C[C@@](N)(CF)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ODC1 P11926 2/20 0.53
GABRR1 P24046 1/20 0.34
ARG1 P05089 1/20 0.32
ARG2 P78540 1/20 0.32
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
CYP1A2 P05177 1/20 0.32
THRB P10828 1/20 0.32
KMT2A Q03164 1/20 0.32
GLRA1 P23415 1/20 0.32
SLC6A9 P48067 1/20 0.32
OR51E2 Q9H255 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11097504 1.00 ODC1 (0.53) ODC1GABRR1ARG1ARG2MEN1
SCHEMBL10924168 1.00 ODC1 (0.53) ODC1GABRR1ARG1ARG2MEN1
SCHEMBL10926218 0.83 ODC1 (0.55) ODC1ARG1ARG2MEN1ALDH1A1
SCHEMBL10925216 0.79 ODC1 (0.60) ODC1GABRR1ARG1ARG2MEN1
SCHEMBL10925004 0.79 ODC1 (0.50) ODC1ARG1ARG2MEN1ALDH1A1
Hydrochloric Acid SCHEMBL10927309 0.78 ODC1 (0.48) ODC1ARG1ARG2
Hydrochloric Acid SCHEMBL28104635 0.76 ODC1 (0.60) ODC1ARG1ARG2MEN1ALDH1A1
SCHEMBL10925953 0.72 ODC1 (0.52) ODC1MEN1ALDH1A1CYP1A2THRB
SCHEMBL349828 0.72 GABRR1 (0.40) ODC1GABRR1ALDH1A1GLRA1SLC6A9
SCHEMBL10960409 0.71 ODC1 (0.46) ODC1GABRR1MEN1ALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0046710-B1 PREPARATION OF AMINOACETONITRILE DERIVATIVES MERRELL TORAUDE ET COMPAGNIE (FR) 1984-06-13 EP disclosed
US-4405530-A Process for preparing fluorinated amino-nitriles MERRELL TORAUDE ET COMPAGNIE (FR) 1983-09-20 US disclosed