Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.61 |
| ▸ | NQO2 | P16083 | 3/20 | 0.61 |
| ▸ | PARG | Q86W56 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | WEE1 | P30291 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.44 |
| ▸ | BRD1 | O95696 | 1/20 | 0.44 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9869325 | 0.86 | KDM4E (0.61) | KDM4ENQO2PARGKAT2BHSD17B10 | |
| SCHEMBL12090570 | 0.81 | NQO2 (0.65) | KDM4ENQO2PARGKAT2BBRD1 | |
| SCHEMBL16292510 | 0.79 | NQO2 (0.61) | KDM4ENQO2PARGKAT2BBRD1 | |
| SCHEMBL30349904 | 0.79 | NQO2 (0.61) | KDM4ENQO2PARGKAT2BBRD1 | |
| SCHEMBL21979134 | 0.79 | NQO2 (0.61) | KDM4ENQO2PARGKAT2BBRD1 | |
| SCHEMBL15564817 | 0.79 | NQO2 (0.61) | KDM4ENQO2PARGKAT2BBRD1 | |
| SCHEMBL17576254 | 0.79 | NQO2 (0.61) | KDM4ENQO2PARGKAT2BBRD1 | |
| SCHEMBL19330830 | 0.78 | MAPT (0.55) | KDM4ENQO2ALOX5PTGS1PTGS2 | |
| SCHEMBL24716706 | 0.78 | NQO2 (0.55) | KDM4ENQO2PARGKAT2BBRD1 | |
| SCHEMBL16189690 | 0.77 | KDM4E (0.54) | KDM4ENQO2KAT2BHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4427680-A | ANTHISTAMINES | BOEHRINGER MANNHEIM GMBH (DE) | 1984-01-24 | — | — | US | disclosed |
| US-4330549-A | Coumarins connected via an oxyalkyl group with a piperidine ring having anti-allergic action | BOEHRINGER MANNHEIM GMBH (DE) | 1982-05-18 | — | — | US | disclosed |
| EP-0013894-B1 | ARYLETHERS, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1982-02-03 | — | — | EP | disclosed |
| EP-0006506-B1 | CARBOSTYRILE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1981-09-16 | — | — | EP | disclosed |
| US-4234585-A | ANTIALLERGENS, HYPOTENSIVE | BOEHRINGER MANNHEIM GMBH (DE) | 1980-11-18 | — | — | US | disclosed |
| EP-0006506-A1 | Carbostyrile derivatives, processes for their preparation and pharmaceutical compositions containing them | Roche Diagnostics GmbH (DE) | 1980-01-09 | — | — | EP | disclosed |