Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.61 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11330160 | 0.90 | PLCG1 (0.61) | PLCG1NAPEPLDKMT2AMEN1ALDH1A1 | |
| SCHEMBL11330163 | 0.90 | PLCG1 (0.61) | PLCG1NAPEPLDKMT2AMEN1ALDH1A1 | |
| SCHEMBL11305923 | 0.89 | PLCG1 (0.66) | PLCG1NAPEPLDKMT2AMEN1ALDH1A1 | |
| SCHEMBL11101773 | 0.89 | PLCG1 (0.66) | PLCG1NAPEPLDKMT2AMEN1ALDH1A1 | |
| SCHEMBL11674261 | 0.88 | PLCG1 (0.59) | PLCG1NAPEPLDKMT2AMEN1ALDH1A1 | |
| SCHEMBL11674265 | 0.88 | PLCG1 (0.59) | PLCG1NAPEPLDKMT2AMEN1ALDH1A1 | |
| SCHEMBL11729128 | 0.88 | PLCG1 (0.54) | PLCG1ALDH1A1L3MBTL1TDP1MAPT | |
| SCHEMBL11729123 | 0.88 | PLCG1 (0.54) | PLCG1ALDH1A1L3MBTL1TDP1MAPT | |
| SCHEMBL11104711 | 0.86 | PLCG1 (0.67) | PLCG1NAPEPLDALDH1A1L3MBTL1RAB9A | |
| SCHEMBL11727875 | 0.86 | PLCG1 (0.67) | PLCG1NAPEPLDKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0014567-B1 | PROCESSES FOR PREPARATION OF BETA-LACTAM COMPOUNDS | ELI LILLY AND COMPANY (US) | 1984-01-18 | — | — | EP | disclosed |
| US-4271305-A | ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1981-06-02 | — | — | US | disclosed |
| US-4226986-A | 7-ACYLAMINO-3-HYDROXY-3-CEPHEM COMPOUND, TRIARYL PHOSPHITE DIHALIDE | ELI LILLY AND COMPANY (US) | 1980-10-07 | — | — | US | disclosed |
| EP-0014567-A1 | Processes for preparation of beta-lactam compounds | ELI LILLY AND COMPANY (US) | 1980-08-20 | — | — | EP | disclosed |