SCHEMBL11098941

SCHEMBL11098941

CCC(C)(CC(=O)C(C)C)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.55
HIF1A Q16665 1/20 0.55
MAPT P10636 2/20 0.49
ALDH1A1 P00352 1/20 0.49
KMT2A Q03164 2/20 0.47
MEN1 O00255 1/20 0.47
CYP1A2 P05177 2/20 0.43
CYP2D6 P10635 2/20 0.43
KIF11 P52732 4/20 0.42
GRIN2D O15399 2/20 0.39
GRIN1 Q05586 2/20 0.39
GRIN2A Q12879 2/20 0.39
GRIN2B Q13224 2/20 0.39
GRIN2C Q14957 2/20 0.39
OPRM1 P35372 2/20 0.39
CACNA1F O60840 1/20 0.39
ABCB1 P08183 1/20 0.39
CYP2B6 P20813 1/20 0.39
DRD4 P21917 1/20 0.39
DRD3 P35462 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3742631 0.82 CYP2C19 (0.81) CYP2C19HIF1AMAPTALDH1A1KMT2A
SCHEMBL27165465 0.81 CYP2C19 (0.52) CYP2C19HIF1AMAPTKMT2ACYP1A2
SCHEMBL20608224 0.80 CYP2C19 (0.60) CYP2C19HIF1AMAPTALDH1A1KMT2A
SCHEMBL10975577 0.80 CYP2C19 (0.50) CYP2C19HIF1AMAPTALDH1A1KMT2A
SCHEMBL20608223 0.80 CYP2C19 (0.60) CYP2C19HIF1AMAPTALDH1A1KMT2A
SCHEMBL19292592 0.76 CYP2C19 (0.55) CYP2C19HIF1AMAPTALDH1A1KMT2A
SCHEMBL27538206 0.75 CYP2C19 (0.53) CYP2C19HIF1AMAPTALDH1A1KMT2A
SCHEMBL10808021 0.74 CYP2C19 (0.54) CYP2C19HIF1AMAPTALDH1A1KMT2A
SCHEMBL599044 0.74 CYP2C19 (0.54) CYP2C19HIF1AMAPTALDH1A1KMT2A
SCHEMBL4488702 0.72 CYP2C19 (0.50) CYP2C19HIF1AMAPTALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0129448-A1 Process for selectively extracting copper using 4-acyl(3H)-pyrazol-3-ones SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) 1984-12-27 EP claimed
EP-0129448-A1 Process for selectively extracting copper using 4-acyl(3H)-pyrazol-3-ones SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) 1984-12-27 EP disclosed