Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 3/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11099155 | 1.00 | KMT2A (0.44) | KMT2AHTTSMN1; SMN2TDP1MAPT | |
| SCHEMBL11105492 | 0.96 | KMT2A (0.43) | KMT2AHTTSMN1; SMN2TDP1MAPT | |
| SCHEMBL11105488 | 0.96 | KMT2A (0.43) | KMT2AHTTSMN1; SMN2TDP1MAPT | |
| SCHEMBL8046575 | 0.96 | HTT (0.47) | KMT2AHTTSMN1; SMN2TDP1MAPT | |
| SCHEMBL8045924 | 0.96 | HTT (0.47) | KMT2AHTTSMN1; SMN2TDP1MAPT | |
| SCHEMBL11106581 | 0.95 | KMT2A (0.42) | KMT2AHTTSMN1; SMN2TDP1MAPT | |
| SCHEMBL11102482 | 0.95 | KMT2A (0.42) | KMT2AHTTSMN1; SMN2TDP1MAPT | |
| SCHEMBL11102159 | 0.95 | KMT2A (0.42) | KMT2AHTTSMN1; SMN2TDP1MAPT | |
| SCHEMBL11102477 | 0.95 | KMT2A (0.42) | KMT2AHTTSMN1; SMN2TDP1MAPT | |
| SCHEMBL11102162 | 0.95 | KMT2A (0.42) | KMT2AHTTSMN1; SMN2TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4473487-A | 4-Fluorobiphenyl derivatives, their preparation, and dielectrics and electro-optical display element containing them | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1984-09-25 | — | — | US | disclosed |