Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.70 |
| ▸ | MEN1 | O00255 | 6/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.70 |
| ▸ | HTT | P42858 | 3/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.70 |
| ▸ | HPGD | P15428 | 2/20 | 0.70 |
| ▸ | HBB | P68871 | 1/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | KDM1A | O60341 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25179738 | 0.91 | NPSR1 (0.68) | MAPTMEN1KMT2AKDM4EHTT | |
| SCHEMBL2287907 | 0.90 | NPSR1 (0.63) | MAPTMEN1KMT2AKDM4EHTT | |
| SCHEMBL11217129 | 0.86 | NPSR1 (0.63) | MAPTMEN1KMT2AKDM4EHTT | |
| SCHEMBL25186625 | 0.83 | MAPT (0.66) | MAPTMEN1KMT2AKDM4EHTT | |
| SCHEMBL30416772 | 0.83 | MAPT (0.66) | MAPTMEN1KMT2AKDM4EHTT | |
| SCHEMBL29357684 | 0.83 | MAPT (1.00) | MAPTMEN1KMT2AKDM4EHTT | |
| SCHEMBL37700 | 0.83 | MAPT (1.00) | MAPTMEN1KMT2AKDM4EHTT | |
| SCHEMBL19757194 | 0.82 | NPSR1 (0.65) | MAPTMEN1KMT2AKDM4EHTT | |
| Water SCHEMBL28844053 | 0.82 | MAPT (0.97) | MAPTMEN1KMT2AKDM4EHTT | |
| Iodide SCHEMBL33722025 | 0.82 | MAPT (0.97) | MAPTMEN1KMT2AKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0037975-B1 | SULFUR DYES OF THE CARBAZOLE SERIES, THEIR PREPARATION AND APPLICATION, AS WELL AS INTERMEDIATE COMPOUNDS | CASSELLA Aktiengesellschaft (DE) | 1984-07-04 | — | — | EP | disclosed |
| EP-0037975-A1 | Sulfur dyes of the carbazole series, their preparation and application, as well as intermediate compounds | CASSELLA Aktiengesellschaft (DE) | 1981-10-21 | — | — | EP | disclosed |