Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.71 |
| ▸ | APP | P05067 | 1/20 | 0.63 |
| ▸ | HTR1A | P08908 | 2/20 | 0.56 |
| ▸ | HTR2C | P28335 | 2/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.56 |
| ▸ | HTR7 | P34969 | 1/20 | 0.56 |
| ▸ | HTR6 | P50406 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | PYGL | P06737 | 5/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11099216 | 1.00 | EGFR (0.71) | EGFRAPPHTR1AHTR2CHTR2A | |
| SCHEMBL8757222 | 0.86 | EGFR (0.73) | EGFRAPPHTR1AHTR2CHTR2A | |
| SCHEMBL8756520 | 0.86 | EGFR (0.73) | EGFRAPPHTR1AHTR2CHTR2A | |
| SCHEMBL8757218 | 0.86 | EGFR (0.73) | EGFRAPPHTR1AHTR2CHTR2A | |
| SCHEMBL8756511 | 0.86 | EGFR (0.73) | EGFRAPPHTR1AHTR2CHTR2A | |
| SCHEMBL8757229 | 0.86 | EGFR (0.73) | EGFRAPPHTR1AHTR2CHTR2A | |
| SCHEMBL8756506 | 0.86 | EGFR (0.73) | EGFRAPPHTR1AHTR2CHTR2A | |
| N-Dodecylcinnamamide SCHEMBL16596238 | 0.84 | EGFR (1.00) | EGFRAPPHTR1AHTR2CHTR2A | |
| N-Dodecylcinnamamide SCHEMBL28975087 | 0.84 | EGFR (1.00) | EGFRAPPHTR1AHTR2CHTR2A | |
| N-Octylcinnamamide SCHEMBL10706126 | 0.84 | EGFR (1.00) | EGFRAPPHTR1AHTR2CHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0047119-B1 | CARBOXAMIDE COMPOUNDS AS SRS-A ANTAGONISTS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, PROCESSES FOR THE PREPARATION, AND INTERMEDIATES USEFUL THEREIN | PFIZER INC. (US) | 1984-05-09 | — | — | EP | disclosed |
| EP-0050977-B1 | CARBOXAMIDE COMPOUNDS AS SRS-A ANTAGONISTS AND A PROCESS FOR PRODUCING SAME | PFIZER INC. (US) | 1983-09-14 | — | — | EP | disclosed |
| US-4343813-A | ANTIANAPHYLACTIC AGENTS | PFIZER INC. (US) | 1982-08-10 | — | — | US | disclosed |
| US-4331683-A | SENSITIZATION, ANTIALLERGENS | PFIZER INC. (US) | 1982-05-25 | — | — | US | disclosed |
| EP-0050977-A1 | Carboxamide compounds as SRS-A antagonists and a process for producing same | PFIZER INC. (US) | 1982-05-05 | — | — | EP | disclosed |
| EP-0047119-A1 | Carboxamide compounds as SRS-A antagonists, pharmaceutical compositions containing them, processes for the preparation, and intermediates useful therein | PFIZER INC. (US) | 1982-03-10 | — | — | EP | disclosed |
| US-4296120-A | ANTIANAPHYLACTIC | PFIZER INC. (US) | 1981-10-20 | — | — | US | disclosed |
| US-4296129-A | ANTIAASTHMATIC INHIBITOR OF SLOW-REACTING SUBSTANCE OF ANAPHYLAXIS | PFIZER, INC. (US) | 1981-10-20 | — | — | US | disclosed |