⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6259313 | 0.92 | — | — | |
| SCHEMBL262534 | 0.74 | — | — | |
| SCHEMBL6258862 | 0.74 | — | — | |
| SCHEMBL313750 | 0.74 | — | — | |
| SCHEMBL153189 | 0.74 | — | — | |
| SCHEMBL150206 | 0.72 | — | — | |
| SCHEMBL19280743 | 0.72 | CYP1A2 (0.39) | — | |
| SCHEMBL8197417 | 0.72 | CYP1A2 (0.39) | — | |
| SCHEMBL18828533 | 0.72 | CYP1A2 (0.39) | — | |
| SCHEMBL10457078 | 0.72 | CYP1A2 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7202235-B2 | Tetracycline compounds for treatment of cryptosporidium parvum related disorders | TRUSTEES OF TUFTS COLLEGE (US) | 2007-04-10 | — | — | US | claimed |
| US-20050215532-A1 | Tetracycline compounds for treatment of cryptosporidium parvum related disorders | TRUSTEES OF TUFTS COLLEGE (US) | 2005-09-29 | — | — | US | claimed |
| EP-1263442-A1 | TETRACYCLINE COMPOUNDS FOR TREATMENT OF i CRYPTOSPORIDIUM PARVUM /i RELATED DISORDERS | TRUSTEES OF TUFTS COLLEGE (US) | 2002-12-11 | — | — | EP | claimed |
| US-20020115644-A1 | Tetracycline compounds for treatment of Cryptosporidium parvum related disorders | PARATEK PHARMACEUTICALS, INC. | 2002-08-22 | — | — | US | claimed |
| WO-2001052858-A1 | TETRACYCLINE COMPOUNDS FOR TREATMENT OF CRYPTOSPORIDIUM PARVUM RELATED DISORDERS | TRUSTEES OF TUFTS COLLEGE (US) | 2001-07-26 | — | — | WO | claimed |
| US-8563526-B2 | Triazole derivatives, their preparation and their application in therapeutics | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2013-10-22 | — | — | US | disclosed |
| US-8466176-B2 | Fungicide hydroximoyl-tetrazole derivatives | BAYER CROPSCIENCE AG (DE) | 2013-06-18 | — | — | US | disclosed |
| US-20110136754-A1 | NOVEL TRIAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS | Institut National De La Sante Et La Recherche Medicale (INSERM) | 2011-06-09 | — | — | US | disclosed |
| US-20110105566-A1 | FUNGICIDE HYDROXIMOYL-TETRAZOLE DERIVATIVES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2011-05-05 | — | — | US | disclosed |
| EP-2279193-A1 | NOVEL TRIAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS | Inserm Transfert (FR) | 2011-02-02 | — | — | EP | disclosed |
| WO-2009133147-A1 | NOVEL TRIAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS | INSERM TRANSFERT (FR) | 2009-11-05 | — | — | WO | disclosed |
| EP-2113508-A1 | Novel triazole nucleoside derivatives, their preparation and their application in therapeutics | INSERM (Institut National de la Santé et de la Recherche Medicale) (FR) | 2009-11-04 | — | — | EP | disclosed |
| EP-0778821-A1 | ORTHO-SUBSTITUTED AROMATIC ETHER COMPOUNDS AND THEIR USE IN PHARMACEUTICAL COMPOSITIONS FOR PAIN RELIEF | ZENECA LIMITED (GB) | 1997-06-18 | — | — | EP | disclosed |
| EP-0773930-A1 | AROMATIC AMINO ETHERS AS PAIN RELIEVING AGENTS | ZENECA LIMITED (GB) | 1997-05-21 | — | — | EP | disclosed |
| EP-0752421-A1 | Ortho-substituted aromatic compounds, containing three (het)aryl moieties, their preparation and their use as prostaglandin E2-(PGE2)-antagonists | ZENECA LIMITED (GB) | 1997-01-08 | — | — | EP | disclosed |
| EP-0733033-A1 | PHARMACEUTICALLY ACTIVE SUBSTITUTED AROMATIC COMPOUNDS | ZENECA LIMITED (GB) | 1996-09-25 | — | — | EP | disclosed |
| WO-1996011902-A1 | PHARMACEUTICALLY ACTIVE SUBSTITUTED AROMATIC COMPOUNDS | ZENECA LIMITED (GB) | 1996-04-25 | — | — | WO | disclosed |
| WO-1996006822-A1 | ORTHO-SUBSTITUTED AROMATIC ETHER COMPOUNDS AND THEIR USE IN PHARMACEUTICAL COMPOSITIONS FOR PAIN RELIEF | ZENECA LIMITED (GB) | 1996-03-07 | — | — | WO | disclosed |
| WO-1996003380-A1 | AROMATIC AMINO ETHERS AS PAIN RELIEVING AGENTS | ZENECA LIMITED (GB) | 1996-02-08 | — | — | WO | disclosed |
| US-5147645-A | Insecticides, miticides, nematocides | BASF AKTIENGESELLSCHAFT (DE) | 1992-09-15 | — | — | US | disclosed |