Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9712857 | 0.76 | CYP1A2 (0.70) | CYP1A2CYP3A4CYP2C19RAB9AGAA | |
| SCHEMBL11099589 | 0.75 | CYP1A2 (0.61) | CYP1A2CYP3A4CYP2C19RAB9AGAA | |
| SCHEMBL10601728 | 0.74 | CYP1A2 (0.57) | CYP1A2CYP3A4CYP2C19RAB9AGAA | |
| SCHEMBL9713785 | 0.74 | CYP1A2 (0.59) | CYP1A2CYP3A4CYP2C19RAB9AGAA | |
| SCHEMBL11248148 | 0.74 | CYP1A2 (0.59) | CYP1A2CYP3A4CYP2C19RAB9AGAA | |
| SCHEMBL9713451 | 0.73 | CYP1A2 (0.59) | CYP1A2CYP3A4CYP2C19RAB9ATP53 | |
| SCHEMBL9712915 | 0.73 | CYP3A4 (0.65) | CYP1A2CYP3A4CYP2C19RAB9AGAA | |
| SCHEMBL9713168 | 0.72 | CYP1A2 (0.64) | CYP1A2CYP3A4CYP2C19RAB9AGAA | |
| SCHEMBL11260078 | 0.71 | CYP1A2 (0.58) | CYP1A2CYP3A4CYP2C19RAB9AGAA | |
| SCHEMBL9713438 | 0.71 | CYP1A2 (0.59) | CYP1A2CYP3A4CYP2C19RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049071-B1 | N-ARYLBENZAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1984-12-19 | — | — | EP | disclosed |
| EP-0049071-A1 | N-arylbenzamide derivatives | ELI LILLY AND COMPANY (US) | 1982-04-07 | — | — | EP | disclosed |