Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19105315 | 0.95 | TSHR (0.53) | TSHRL3MBTL1MAPK1TDP1MEN1 | |
| SCHEMBL28663773 | 0.89 | TSHR (0.56) | TSHRL3MBTL1MAPK1TDP1ALDH1A1 | |
| SCHEMBL28822212 | 0.88 | TSHR (0.59) | TSHRTDP1HPGDLMNACA2 | |
| SCHEMBL250544 | 0.88 | TSHR (0.50) | TSHRL3MBTL1MAPK1TDP1ALDH1A1 | |
| SCHEMBL455720 | 0.85 | TDP1 (0.53) | TSHRL3MBTL1MAPK1TDP1MEN1 | |
| SCHEMBL12537387 | 0.84 | TSHR (0.44) | TSHRTDP1HPGDSMN1; SMN2CA1 | |
| SCHEMBL8937545 | 0.83 | TSHR (0.47) | TSHRL3MBTL1MAPK1TDP1MEN1 | |
| Ammonia Solution, Strong SCHEMBL27849182 | 0.83 | TDP1 (0.51) | TSHRL3MBTL1MAPK1TDP1MEN1 | |
| SCHEMBL11832901 | 0.83 | TDP1 (0.51) | TSHRL3MBTL1MAPK1TDP1MEN1 | |
| SCHEMBL28663774 | 0.83 | TSHR (0.53) | TSHRTDP1ALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4470421-A | SMOKING COMPOSITIONS CONTAINING A POLYMERIZABLE OR POLYMERIZED MALONATE FLAVOR ADDITIVE | PHILIP MORRIS, INCORPORATED (US) | 1984-09-11 | — | — | US | claimed |
| US-4470421-A | SMOKING COMPOSITIONS CONTAINING A POLYMERIZABLE OR POLYMERIZED MALONATE FLAVOR ADDITIVE | PHILIP MORRIS, INCORPORATED (US) | 1984-09-11 | — | — | US | disclosed |
| US-4470421-A | SMOKING COMPOSITIONS CONTAINING A POLYMERIZABLE OR POLYMERIZED MALONATE FLAVOR ADDITIVE | PHILIP MORRIS, INCORPORATED (US) | 1984-09-11 | — | — | US | disclosed |