Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD1 | Q15139 | 2/20 | 0.46 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 15/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | PRKCH | P24723 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11100753 | 0.84 | MAPK14 (0.40) | PRKD1PRKD2MAPK14MAPK10PRKCH | |
| SCHEMBL11102425 | 0.83 | ROCK1 (0.44) | PRKD1MAPK10 | |
| SCHEMBL25095006 | 0.80 | MAPK10 (0.33) | MAPK14MAPK10 | |
| SCHEMBL11097380 | 0.79 | PRKD1 (0.47) | PRKD1PRKD2MAPK14MAPK10PRKCH | |
| SCHEMBL1502132 | 0.79 | PRKD1 (0.44) | PRKD1PRKD2MAPK14MAPK10HRH4 | |
| SCHEMBL11100755 | 0.78 | MAPK14 (0.47) | PRKD1PRKD2MAPK14HRH4 | |
| SCHEMBL11101103 | 0.78 | MAPK14 (0.50) | MAPK14 | |
| SCHEMBL11102704 | 0.77 | HRH4 (0.41) | PRKD1PRKD2MAPK14HRH4 | |
| SCHEMBL11101105 | 0.75 | MAPK14 (0.50) | MAPK14HRH4 | |
| SCHEMBL26550138 | 0.75 | MAPK14 (0.52) | PRKD1PRKD2MAPK14MAPK10PRKCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0051371-B1 | IMIDAZOLYLPYRIDINE THERAPEUTIC AGENTS | PFIZER INC. (US) | 1984-08-29 | — | — | EP | disclosed |
| EP-0051371-A2 | Imidazolylpyridine therapeutic agents | PFIZER INC. (US) | 1982-05-12 | — | — | EP | disclosed |
| US-4302464-A | ANTIULCER AGENTS, ANTI-H2-HISTAMINES | PFIZER INC. (US) | 1981-11-24 | — | — | US | disclosed |