Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.54 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11100460 | 1.00 | CYP4F2 (0.54) | CYP4F2CYP4A11LMNAMAPK1SLC7A5 | |
| SCHEMBL31008831 | 0.86 | CYP4F2 (0.54) | CYP4F2CYP4A11LMNASLC7A5ALDH1A1 | |
| SCHEMBL28408150 | 0.81 | CYP4F2 (0.53) | CYP4F2CYP4A11LMNASLC7A5ALDH1A1 | |
| SCHEMBL13849473 | 0.81 | CYP4F2 (0.53) | CYP4F2CYP4A11LMNASLC7A5ALDH1A1 | |
| SCHEMBL7076991 | 0.81 | CYP4F2 (0.53) | CYP4F2CYP4A11LMNASLC7A5ALDH1A1 | |
| SCHEMBL4113212 | 0.81 | CYP4F2 (0.76) | CYP4F2CYP4A11LMNAALDH1A1GAA | |
| SCHEMBL2060365 | 0.80 | CYP4F2 (0.59) | CYP4F2CYP4A11LMNAALDH1A1TSHR | |
| SCHEMBL13849449 | 0.79 | CYP4F2 (0.54) | CYP4F2CYP4A11LMNAALDH1A1GAA | |
| SCHEMBL17966287 | 0.79 | CYP4F2 (0.58) | CYP4F2CYP4A11LMNAALDH1A1GAA | |
| SCHEMBL9782118 | 0.78 | CYP4F2 (0.53) | CYP4F2CYP4A11LMNASLC7A5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0053408-B1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED GLYOXYLIC ACID DERIVATIVES | STAMICARBON B.V. (NL) | 1984-10-17 | — | — | EP | disclosed |
| EP-0053408-A1 | Process for the preparation of substituted glyoxylic acid derivatives | STAMICARBON B.V. (NL) | 1982-06-09 | — | — | EP | disclosed |