Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | RARA | P10276 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 4/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | ACR | P10323 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11101668 | 1.00 | RARB (0.56) | RARBMAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL11222777 | 1.00 | RARB (0.56) | RARBMAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL11100407 | 0.96 | MAPT (0.60) | RARBMAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL11097180 | 0.96 | MAPT (0.60) | RARBMAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL11101485 | 0.95 | MAPT (0.58) | RARBMAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL11104529 | 0.95 | MAPT (0.58) | RARBMAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL11104273 | 0.95 | MAPT (0.58) | RARBMAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL11102964 | 0.95 | MAPT (0.58) | RARBMAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL11107081 | 0.95 | MAPT (0.58) | RARBMAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL11547222 | 0.93 | RARB (0.64) | RARBMAPTSMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4473487-A | 4-Fluorobiphenyl derivatives, their preparation, and dielectrics and electro-optical display element containing them | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1984-09-25 | — | — | US | disclosed |