Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.68 |
| ▸ | TTR | P02766 | 1/20 | 0.68 |
| ▸ | PPOX | P50336 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 7/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PYGL | P06737 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10500001 | 0.96 | MEN1 (0.73) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL10500810 | 0.94 | MEN1 (0.73) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL10499965 | 0.93 | TDP1 (0.77) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL11110522 | 0.91 | MEN1 (0.66) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL11109698 | 0.91 | MEN1 (0.66) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL11265405 | 0.90 | TDP1 (0.74) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL10501353 | 0.90 | TDP1 (0.74) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL10919922 | 0.90 | TDP1 (0.64) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL9338282 | 0.89 | MEN1 (0.70) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL11024642 | 0.89 | MEN1 (0.70) | MEN1KMT2ATDP1TTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435588-A | 2'-CHLORO-4'-TRIFLUOROMETHYL-PHENOXY-3-BENZOATE DERIVATIVES | GAF CORPORATION (US) | 1984-03-06 | — | — | US | disclosed |
| EP-0066106-A1 | New phenoxybenzoates, process for preparing these compounds, compositions containing them and method of use | GAF CORPORATION (US) | 1982-12-08 | — | — | EP | disclosed |