Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GUSB | P08236 | 2/20 | 0.40 |
| ▸ | GBA2 | Q9HCG7 | 6/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11108682 | 1.00 | GBA1 (0.50) | GBA1ALDH1A1TDP1SPHK2SPHK1 | |
| SCHEMBL11098588 | 1.00 | GBA1 (0.50) | GBA1ALDH1A1TDP1SPHK2SPHK1 | |
| SCHEMBL15618283 | 1.00 | GBA1 (0.50) | GBA1ALDH1A1TDP1SPHK2SPHK1 | |
| SCHEMBL15618295 | 1.00 | GBA1 (0.50) | GBA1ALDH1A1TDP1SPHK2SPHK1 | |
| SCHEMBL11110339 | 1.00 | GBA1 (0.50) | GBA1ALDH1A1TDP1SPHK2SPHK1 | |
| SCHEMBL15618347 | 1.00 | GBA1 (0.50) | GBA1ALDH1A1TDP1SPHK2SPHK1 | |
| SCHEMBL15618344 | 1.00 | GBA1 (0.50) | GBA1ALDH1A1TDP1SPHK2SPHK1 | |
| SCHEMBL11098591 | 1.00 | GBA1 (0.50) | GBA1ALDH1A1TDP1SPHK2SPHK1 | |
| SCHEMBL15618294 | 1.00 | GBA1 (0.50) | GBA1ALDH1A1TDP1SPHK2SPHK1 | |
| SCHEMBL11097755 | 1.00 | GBA1 (0.50) | GBA1ALDH1A1TDP1SPHK2SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4454123-A | ANTICOAGULANTS, ANTITUMOR AGENTS | SEIKAGAKU KOGYO CO. LTD. (JP) | 1984-06-12 | — | — | US | disclosed |