Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | F13A1 | P00488 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4620051 | 0.86 | KDM4E (0.48) | KDM4EMAPK1HIF1APAOXADRA1A | |
| Acamprosate SCHEMBL41983 | 0.80 | KDM4E (0.65) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL8067563 | 0.80 | KDM4E (0.58) | KDM4EMAPK1HIF1APAOXADRA1A | |
| Acamprosate SCHEMBL6570666 | 0.78 | KDM4E (0.62) | KDM4EMAPK1HIF1APAOXADRA1A | |
| Acamprosate SCHEMBL7639758 | 0.78 | KDM4E (0.62) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL2288196 | 0.78 | KDM4E (0.56) | KDM4EMAPK1HIF1APAOXADRA1A | |
| Acamprosate SCHEMBL347087 | 0.78 | KDM4E (0.62) | KDM4EMAPK1HIF1APAOXADRA1A | |
| Acamprosate SCHEMBL17599929 | 0.78 | KDM4E (0.62) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL26145075 | 0.78 | KDM4E (0.56) | KDM4EMAPK1HIF1APAOXADRA1A | |
| Acamprosate SCHEMBL34472814 | 0.78 | KDM4E (0.62) | KDM4EMAPK1HIF1APAOXADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4448722-A | ACID ADDITION SALTS OF COPPER PHTHALOCYANINE-USED IN DYEING CELLULOSE | THE HILTON-DAVIS CHEMICAL CO. (US) | 1984-05-15 | — | — | US | disclosed |
| US-4379710-A | Novel compositions and processes | STERLING DRUG INC. (US) | 1983-04-12 | — | — | US | disclosed |