Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 9/20 | 0.39 |
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | FASN | P49327 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11110505 | 1.00 | HCRTR2 (0.39) | HCRTR2KDM1AFASNCYP3A4CYP2C9 | |
| SCHEMBL10043261 | 0.90 | FASN (0.39) | HCRTR2KDM1AFASN | |
| SCHEMBL15061084 | 0.87 | HCRTR2 (0.33) | HCRTR2KDM1A | |
| SCHEMBL8110573 | 0.84 | HCRTR2 (0.40) | HCRTR2KDM1A | |
| SCHEMBL8110569 | 0.84 | HCRTR2 (0.40) | HCRTR2KDM1A | |
| SCHEMBL11113547 | 0.83 | CYP2C9 (0.42) | HCRTR2FASNCYP3A4CYP2C9APP | |
| SCHEMBL10043251 | 0.83 | FASN (0.45) | HCRTR2FASNCYP3A4CYP2C9APP | |
| SCHEMBL11113543 | 0.83 | CYP2C9 (0.42) | HCRTR2FASNCYP3A4CYP2C9APP | |
| SCHEMBL10043221 | 0.83 | FASN (0.45) | HCRTR2FASNCYP3A4CYP2C9APP | |
| SCHEMBL10922707 | 0.82 | FASN (0.46) | HCRTR2FASNCYP3A4CYP2C9APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0064193-B1 | 4,4'-BIS-(CYCLOHEXYL)-BIPHENYL DERIVATIVES THAT CONTAIN FLUORINE, DIELECTRICS CONTAINING THEM, AND ELECTRO-OPTICAL INDICATOR ELEMENT | MERCK PATENT GmbH (DE) | 1984-07-25 | — | — | EP | disclosed |
| US-4419264-A | Fluorine-containing 4,4'-bis-(cyclohexyl)-biphenyl derivatives, and dielectrics and electro-optical display elements containing them | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1983-12-06 | — | — | US | disclosed |
| EP-0064193-A1 | 4,4'-Bis-(cyclohexyl)-biphenyl derivatives that contain fluorine, dielectrics containing them, and electro-optical indicator element | MERCK PATENT GmbH (DE) | 1982-11-10 | — | — | EP | disclosed |