Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.43 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11100351 | 1.00 | TSHR (0.72) | TSHRHSD17B10ALDH1A1KDM4EHPGD | |
| SCHEMBL11109906 | 1.00 | TSHR (0.72) | TSHRHSD17B10ALDH1A1KDM4EHPGD | |
| SCHEMBL11103216 | 1.00 | TSHR (0.72) | TSHRHSD17B10ALDH1A1KDM4EHPGD | |
| SCHEMBL11103383 | 0.98 | TSHR (0.69) | TSHRHSD17B10ALDH1A1KDM4EHPGD | |
| SCHEMBL11104834 | 0.94 | TSHR (0.67) | TSHRHSD17B10ALDH1A1KDM4EHPGD | |
| SCHEMBL11102988 | 0.88 | TSHR (0.61) | TSHRHSD17B10ALDH1A1HPGDCYP2A6 | |
| SCHEMBL25187484 | 0.84 | HSD17B10 (1.00) | TSHRHSD17B10ALDH1A1KDM4EHPGD | |
| SCHEMBL8022050 | 0.84 | HSD17B10 (1.00) | TSHRHSD17B10ALDH1A1KDM4EHPGD | |
| SCHEMBL25190474 | 0.84 | HSD17B10 (1.00) | TSHRHSD17B10ALDH1A1KDM4EHPGD | |
| SCHEMBL1325933 | 0.84 | HSD17B10 (1.00) | TSHRHSD17B10ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4431564-A | 4'-/2-ALKYLOXYETHYL/-4-CYANOBI-OR TERPHENYLS; DISPLAYING; IODINATION AND CYANATION THE ESTER DERIVATIVE | CHISSO CORPORATION (JP) | 1984-02-14 | — | — | US | disclosed |