Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | HTR2A | P28223 | 3/20 | 0.49 |
| ▸ | HRH1 | P35367 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | THPO | P40225 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11104755 | 0.98 | KDM4E (0.50) | KDM4EHTR2AHRH1LMNATP53 | |
| SCHEMBL11105855 | 0.92 | HTR2A (0.42) | KDM4EHTR2AHRH1LMNATP53 | |
| Hydrochloric Acid SCHEMBL11105989 | 0.91 | KDM4E (0.43) | KDM4EHTR2AHRH1LMNATP53 | |
| SCHEMBL11105864 | 0.85 | KDM4E (0.42) | KDM4EHTR2AHRH1LMNATP53 | |
| SCHEMBL11110785 | 0.85 | SLC6A2 (0.42) | KDM4EHTR2AHRH1LMNATP53 | |
| SCHEMBL11108215 | 0.85 | KDM4E (0.42) | KDM4EHTR2AHRH1LMNATP53 | |
| SCHEMBL11105739 | 0.85 | KDM4E (0.42) | KDM4EHTR2AHRH1LMNATP53 | |
| SCHEMBL11108509 | 0.85 | SLC6A2 (0.42) | KDM4EHTR2AHRH1LMNATP53 | |
| SCHEMBL11105871 | 0.85 | KDM4E (0.42) | KDM4EHTR2AHRH1LMNATP53 | |
| SCHEMBL11106078 | 0.85 | KDM4E (0.42) | KDM4EHTR2AHRH1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4463001-A | ANTIULCER AGENTS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1984-07-31 | — | — | US | disclosed |