Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | CDK1 | P06493 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10914851 | 0.94 | GAA (0.53) | GAACDK1MAPTTP53GLA | |
| SCHEMBL10455714 | 0.94 | GAA (0.53) | GAACDK1MAPTTP53GLA | |
| SCHEMBL10460094 | 0.92 | GAA (0.52) | GAACDK1MAPTTP53GLA | |
| SCHEMBL10458327 | 0.91 | GAA (0.51) | GAACDK1MAPTTP53GLA | |
| SCHEMBL10455589 | 0.89 | GAA (0.53) | GAACDK1MAPTTP53GLA | |
| SCHEMBL11175919 | 0.88 | MAPT (0.46) | GAACDK1MAPTKMT2AKDM4E | |
| SCHEMBL10743535 | 0.87 | GAA (0.45) | GAAMAPTKMT2AKDM4ENPC1 | |
| SCHEMBL11000316 | 0.86 | GAA (0.57) | GAACDK1MAPTTP53GLA | |
| SCHEMBL10616134 | 0.86 | GAA (0.67) | GAACDK1MAPTTP53GLA | |
| SCHEMBL9467729 | 0.85 | GAA (0.53) | GAACDK1MAPTTP53GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0023422-B1 | HERBICIDAL SULFONAMIDES, PREPARATION AND USE THEREOF, AND COMPOSITIONS CONTAINING THEM | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-02-22 | — | — | EP | claimed |