Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7345447 | 1.00 | EPHX1 (0.45) | EPHX1HIF1AALDH1A1SIGMAR1HSD17B10 | |
| SCHEMBL2216881 | 1.00 | — | — | |
| SCHEMBL15829236 | 1.00 | EPHX1 (0.45) | EPHX1HIF1AALDH1A1SIGMAR1HSD17B10 | |
| SCHEMBL18869274 | 1.00 | EPHX1 (0.45) | EPHX1HIF1AALDH1A1SIGMAR1HSD17B10 | |
| SCHEMBL10873364 | 1.00 | EPHX1 (0.45) | EPHX1HIF1AALDH1A1SIGMAR1HSD17B10 | |
| SCHEMBL16007530 | 1.00 | EPHX1 (0.45) | EPHX1HIF1AALDH1A1SIGMAR1HSD17B10 | |
| SCHEMBL6676683 | 1.00 | — | — | |
| Water SCHEMBL2965632 | 0.97 | EPHX1 (0.43) | EPHX1HIF1AALDH1A1SIGMAR1 | |
| SCHEMBL9351268 | 0.96 | — | — | |
| Water SCHEMBL2318146 | 0.94 | EPHX1 (0.41) | EPHX1HIF1AALDH1A1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2623499-B1 | 1,2,4-triazolone derivative | TAISHO PHARMACEUTICAL CO LTD (JP) | 2015-04-22 | — | — | EP | disclosed |
| US-8669248-B1 | Adenine inhibitors of HSP90 | MONTANA JOHN (GB) | 2014-03-11 | — | — | US | disclosed |
| EP-0046189-B1 | ISOXAZOLINO-AZOXY COMPOUNDS AND PROCESS FOR THEIR PREPARATION | BASF Aktiengesellschaft (DE) | 1984-01-04 | — | — | EP | disclosed |