Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.68 |
| ▸ | ATM | Q13315 | 3/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | CASP1 | P29466 | 2/20 | 0.49 |
| ▸ | CASP7 | P55210 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | AKT1 | P31749 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9444261 | 0.98 | KDM4E (0.69) | KDM4EATMHTTMAPTKMT2A | |
| SCHEMBL619914 | 0.97 | KDM4E (0.64) | KDM4EATMHTTMAPTKMT2A | |
| SCHEMBL471516 | 0.88 | HDAC3 (0.63) | KDM4EATMHTTMAPTKMT2A | |
| SCHEMBL11114046 | 0.88 | KDM4E (0.63) | KDM4EATMHTTMAPTKMT2A | |
| SCHEMBL1933585 | 0.86 | KDM4E (0.61) | KDM4EATMHTTMAPTKMT2A | |
| SCHEMBL619664 | 0.84 | KDM4E (0.63) | KDM4EATMHTTMAPTKMT2A | |
| SCHEMBL1829468 | 0.84 | KDM4E (0.68) | KDM4EATMHTTMAPTKMT2A | |
| SCHEMBL1828856 | 0.83 | KDM4E (0.69) | KDM4EATMHTTMAPTKMT2A | |
| SCHEMBL1821870 | 0.83 | KDM4E (0.69) | KDM4EATMHTTMAPTKMT2A | |
| SCHEMBL471249 | 0.81 | HDAC3 (0.61) | KDM4EATMHTTMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4479007-A | Chroman-4-ones and process for preparing same | BAYER AKTIENGESELLSCHAFT (DE) | 1984-10-23 | — | — | US | disclosed |
| US-4415741-A | REACTING O-HYDROXYACETOPHENONE AND CYCLOPENTANONE | BAYER AKTIENGESELLSCHAFT (DE) | 1983-11-15 | — | — | US | disclosed |
| US-4185112-A | INSECTICIDES, MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-01-22 | — | — | US | disclosed |