Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1B | O75688 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14614764 | 1.00 | PPM1B (0.46) | PPM1BPTPN1PPP1CCCYP2D6LMNA | |
| SCHEMBL11111768 | 1.00 | PPM1B (0.46) | PPM1BPTPN1PPP1CCCYP2D6LMNA | |
| SCHEMBL4415431 | 0.92 | PPM1B (0.43) | PPM1BPTPN1PPP1CCLMNAMAPT | |
| SCHEMBL9083280 | 0.92 | PPM1B (0.43) | PPM1BPTPN1PPP1CCLMNAMAPT | |
| SCHEMBL4521342 | 0.92 | PPM1B (0.43) | PPM1BPTPN1PPP1CCLMNAMAPT | |
| SCHEMBL14400889 | 0.92 | PPM1B (0.43) | PPM1BPTPN1PPP1CCLMNAMAPT | |
| SCHEMBL14393314 | 0.92 | PPM1B (0.43) | PPM1BPTPN1PPP1CCLMNAMAPT | |
| SCHEMBL9083292 | 0.92 | PPM1B (0.43) | PPM1BPTPN1PPP1CCLMNAMAPT | |
| Hydrochloric Acid SCHEMBL4415435 | 0.90 | PPM1B (0.42) | PPM1BPTPN1PPP1CCCYP2D6LMNA | |
| Hydrochloric Acid SCHEMBL4415434 | 0.90 | PPM1B (0.42) | PPM1BPTPN1PPP1CCCYP2D6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4483991-A | Hypotensive agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1984-11-20 | — | — | US | disclosed |