Known targets — ChEMBL curated mechanism
SLC6A2SLC6A3SSTR1SSTR2SSTR3SSTR5
The experimentally established mechanism targets of Aspartic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.36 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.36 |
| ▸ | GRM8 | O00222 | 1/20 | 0.36 |
| ▸ | GRM6 | O15303 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GSR | P00390 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aspartic Acid SCHEMBL693371 | 0.97 | SLC22A6 (0.39) | SLC22A6GABRR1LMNATDP1GRIK1 | |
| Aspartic Acid SCHEMBL5492529 | 0.95 | SLC22A6 (0.38) | SLC22A6GABRR1LMNATDP1GRIK1 | |
| Aspartic Acid SCHEMBL10597783 | 0.95 | SLC22A6 (0.38) | SLC22A6GABRR1LMNATDP1GRIK1 | |
| Aspartic Acid SCHEMBL4018865 | 0.95 | SLC22A6 (0.38) | SLC22A6GABRR1LMNATDP1GRIK1 | |
| Aspartic Acid SCHEMBL4019503 | 0.95 | SLC22A6 (0.38) | SLC22A6GABRR1LMNATDP1GRIK1 | |
| Aspartic Acid SCHEMBL10599250 | 0.95 | SLC22A6 (0.38) | SLC22A6GABRR1LMNATDP1GRIK1 | |
| Aspartic Acid SCHEMBL10599209 | 0.95 | SLC22A6 (0.38) | SLC22A6GABRR1LMNATDP1GRIK1 | |
| Aspartic Acid SCHEMBL517239 | 0.95 | SLC22A6 (0.38) | SLC22A6GABRR1LMNATDP1GRIK1 | |
| Aspartic Acid SCHEMBL1987594 | 0.95 | SLC22A6 (0.41) | SLC22A6GABRR1LMNATDP1GRIK1 | |
| Aspartic Acid SCHEMBL10456349 | 0.93 | SLC22A6 (0.36) | SLC22A6GABRR1LMNATDP1GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0108937-A2 | Process for the production of amino-dicarboxylic acid-bivalent metal-halogen complexes and novel such complexes | Verla-Pharm Arzneimittelfabrik Apotheker H.J. von Ehrlich GmbH & Co. KG (DE) | 1984-05-23 | — | — | EP | claimed |