Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA4 | P22748 | 3/20 | 0.44 |
| ▸ | CA6 | P23280 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HLCS | P50747 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3834144 | 1.00 | KDM4E (0.45) | KDM4ECA1CA2CA4CA6 | |
| SCHEMBL3818006 | 0.98 | KDM4E (0.46) | KDM4ECA1CA2CA4CA6 | |
| SCHEMBL7911743 | 0.98 | KDM4E (0.46) | KDM4ECA1CA2CA4CA6 | |
| SCHEMBL11107701 | 0.94 | NPC1 (0.44) | KDM4ECA1CA2CA4CA6 | |
| SCHEMBL3817854 | 0.93 | KDM4E (0.47) | KDM4ECA1CA2CA4CA6 | |
| SCHEMBL11595453 | 0.91 | KDM4E (0.49) | KDM4ECA1CA2CA4CA6 | |
| SCHEMBL11058566 | 0.87 | KDM4E (0.50) | KDM4ECA1CA2CA4CA6 | |
| SCHEMBL3819009 | 0.85 | KDM4E (0.50) | KDM4ECA1CA2CA4CA6 | |
| Hydrogen Peroxide SCHEMBL28783701 | 0.83 | NPC1 (0.47) | KDM4ECA1CA2CA4CA6 | |
| SCHEMBL2221778 | 0.83 | KDM4E (0.51) | KDM4ECA1CA2CA4CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0107733-A4 | CYCLOALIPHATIC PHARMACEUTICAL COMPOUNDS. | CBD CORP (US) | 1984-09-13 | — | — | EP | disclosed |
| EP-0107733-A1 | CYCLOALIPHATIC PHARMACEUTICAL COMPOUNDS. | CBD CORP (US) | 1984-05-09 | — | — | EP | disclosed |
| WO-1983004019-A1 | CYCLOALIPHATIC PHARMACEUTICAL COMPOUNDS | CBD CORPORATION (US) | 1983-11-24 | — | — | WO | disclosed |