Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 2/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6582851 | 0.89 | KMT2A (0.52) | MEN1KMT2APOLBL3MBTL1ALDH1A1 | |
| SCHEMBL11112106 | 0.83 | CCR1 (0.46) | MEN1KMT2APOLBMAPK1IDO1 | |
| SCHEMBL7657031 | 0.82 | GAA (0.50) | POLBALDH1A1LMNA | |
| SCHEMBL11198510 | 0.82 | CDK1 (0.42) | CDK1ALDH1A1TDP1CCR1CYP19A1 | |
| SCHEMBL7790487 | 0.80 | MPI (0.44) | MEN1KMT2ATP53ALDH1A1LMNA | |
| SCHEMBL8144605 | 0.80 | CDK1 (0.43) | MEN1KMT2APOLBL3MBTL1TP53 | |
| SCHEMBL1307373 | 0.80 | FERMT2 (0.40) | L3MBTL1CDK1LMNACCR1CYP19A1 | |
| SCHEMBL7655772 | 0.79 | SMN1; SMN2 (0.48) | MEN1KMT2APOLBMAPK1CDK1 | |
| SCHEMBL30516524 | 0.79 | PRSS1 (0.49) | TP53MAPK1CDK1ALDH1A1TDP1 | |
| SCHEMBL2794943 | 0.79 | PRSS1 (0.49) | TP53MAPK1CDK1ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0058868-B1 | DERIVATIVES OF TETRAHYDROPYRIMIDINON, PROCESS FOR THEIR PREPARATION AND HERBICIDES CONTAINING THOSE DERIVATIVES AS ACTIVE PRODUCTS | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1984-04-11 | — | — | EP | disclosed |
| US-4402731-A | Herbicidally active novel substituted tetrahydropyrimidinones | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1983-09-06 | — | — | US | disclosed |
| EP-0058868-A1 | Derivatives of tetrahydropyrimidinon, process for their preparation and herbicides containing those derivatives as active products | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1982-09-01 | — | — | EP | disclosed |