SCHEMBL11113702

SCHEMBL11113702

O=C1C(=O)N2CCNCC12

nearest known ligand 0.54

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 20/20 0.54
HTR2B P41595 18/20 0.54
HTR2A P28223 16/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8358284 0.81 HTR2C (0.54) HTR2CHTR2BHTR2A
SCHEMBL8596101 0.79 HTR2C (0.72) HTR2CHTR2BHTR2A
SCHEMBL29977318 0.77
SCHEMBL8357833 0.76 HTR2C (0.52) HTR2CHTR2BHTR2A
SCHEMBL2161211 0.72 HTR2C (0.57) HTR2CHTR2BHTR2A
SCHEMBL11380531 0.71 HTR2C (1.00) HTR2CHTR2BHTR2A
Hydrochloric Acid SCHEMBL20544769 0.71 HTR2C (0.55) HTR2CHTR2BHTR2A
Hydrochloric Acid SCHEMBL3946104 0.70 HTR2C (0.97) HTR2CHTR2BHTR2A
SCHEMBL30337226 0.69 HTR2C (0.42) HTR2CHTR2BHTR2A
SCHEMBL11377001 0.69 HTR2C (0.74) HTR2CHTR2BHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0023353-B1 SELF-EXTINGUISHING POLYMERIC COMPOSITIONS Montedison S.p.A. (IT) 1984-07-04 EP disclosed
EP-0023353-A1 Self-extinguishing polymeric compositions Montedison S.p.A. (IT) 1981-02-04 EP disclosed