Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | AGXT | P21549 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985150 | 0.87 | IDO1 (0.39) | TSHRMAOBIDO1AGXTCYP1A2 | |
| SCHEMBL3061745 | 0.83 | MEN1 (0.46) | IDO1AGXTCYP1A2CYP1A1CYP1B1 | |
| SCHEMBL18626228 | 0.81 | TSHR (0.54) | TSHRMAOBIDO1AGXTALDH1A1 | |
| SCHEMBL25059945 | 0.80 | ESR1 (0.42) | TSHRMAOBIDO1AGXTALDH1A1 | |
| SCHEMBL2798157 | 0.79 | TSHR (0.57) | TSHRMAOBIDO1AGXTALDH1A1 | |
| SCHEMBL3890177 | 0.79 | FFAR1 (0.49) | TSHRMAOBALDH1A1LMNAL3MBTL1 | |
| SCHEMBL28300975 | 0.78 | CA1 (0.35) | MAOBIDO1AGXTCYP1A2CYP1A1 | |
| SCHEMBL1269173 | 0.78 | IDO1 (0.50) | IDO1ALDH1A1CYP1A2CA2CA9 | |
| SCHEMBL8763411 | 0.77 | CYP1A1 (0.41) | TSHRMAOBIDO1ALDH1A1CYP1A2 | |
| SCHEMBL19821487 | 0.76 | KMT2A (0.37) | IDO1AGXTLMNAL3MBTL1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 307 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114488446-A | Optical cable cladding capable of being repeatedly used and preparation method thereof | 胡从美 | 2022-05-13 | — | — | CN | claimed |
| EP-3841137-A1 | DRYING AGENT FOR MOISTURE-CURING COMPOSITIONS | Covestro Intellectual Property GmbH & Co. KG (DE) | 2021-06-30 | — | — | EP | claimed |
| WO-2020038803-A1 | DRYING AGENT FOR MOISTURE-CURING COMPOSITIONS | COVESTRO DEUTSCHLAND AG (DE) | 2020-02-27 | — | — | WO | claimed |
| CN-104530417-B | A kind of multiple functionalized H types polyethyleneglycol derivative and preparation method thereof | 厦门赛诺邦格生物科技股份有限公司 | 2017-09-08 | — | — | CN | claimed |
| CN-104530415-B | A kind of different functionalization Y types polyethyleneglycol derivative, preparation method and its bio-related substance | 厦门赛诺邦格生物科技股份有限公司 | 2017-09-01 | — | — | CN | claimed |
| CN-101899026-B | Intermediates for the preparation of analogs of halichondrin B | 卫材R&D管理有限公司 | 2016-08-03 | — | — | CN | claimed |
| CN-104530415-A | Hetero-functionalized Y-type polyethylene glycol derivative, preparation method and biologically related substance thereof | XIAMEN SINOPEG BIOTECH INC | 2015-04-22 | — | — | CN | claimed |
| CN-104530417-A | Multifunctional H-type polyethylene glycol derivative and preparation method thereof | XIAMEN SINOPEG BIOTECH INC | 2015-04-22 | — | — | CN | claimed |
| CN-1331846-C | Alpha-cyano benzalcohol and alpha-cyano benzalcohol acetate mixture extraction and separation method | UNIV ZHEJIANG (CN) | 2007-08-15 | — | — | CN | claimed |
| CN-1268755-C | Process for preparing optical active cyanalcohol through enzyme catalysis alcoholysis reaction resolution | UNIV ZHEJIANG (CN) | 2006-08-09 | — | — | CN | claimed |
| US-6576372-B1 | Hydroxy-containing substituent having a dipole moment is coupled to polyurethane through a NHCOO linkage | NISSHINBO INDUSTRIES, INC. (JP) | 2003-06-10 | — | — | US | claimed |
| EP-0132392-B1 | ASYMMETRIC SYNTHESIS OF ALPHA-SUBSTITUTED-ALPHA-CYANOMETHYL ALCOHOLS | ICI AUSTRALIA LIMITED (AU) | 1992-01-02 | — | — | EP | claimed |
| EP-0416338-A2 | Process for the preparation of solutions of polyisocyanates containing isocyanurate groups in solvents for lacquers and their use | BAYER AG (DE) | 1991-03-13 | — | — | EP | claimed |
| US-4985365-A | WITH AN ESTERASE FROM A MICROORGANISM, ASSYMETRIC HYDROLYSIS | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1991-01-15 | — | — | US | claimed |
| EP-0316738-A2 | Process for the preparation of polyisocyanates containing urethane groups | BAYER AG (DE) | 1989-05-24 | — | — | EP | claimed |
| EP-0132392-A2 | Asymmetric synthesis of alpha-substituted-alpha-cyanomethyl alcohols | ICI AUSTRALIA LIMITED (AU) | 1985-01-30 | — | — | EP | claimed |
| EP-0021825-B1 | POLYCAPROLACTONE POLYOL URETHANES AND PROCESSES FOR THEIR PRODUCTION | UNION CARBIDE CORPORATION (US) | 1984-09-26 | — | — | EP | claimed |
| EP-0010675-B1 | WORKING-UP PROCESS OF TOLUYLEN DIISOCYANATE-DISTILLATION RESIDUES AND USE OF THE PRODUCTS THUS OBTAINED AS MOULDABLE MATERIAL OR AS ACTIVE FILLERS, IN PARTICULAR IN THE PRODUCTION OF PANELS AND SHAPED ARTICLES | BAYER AG (DE) | 1983-02-23 | — | — | EP | claimed |
| EP-0047419-A1 | Process for the production of liquid mixtures of compounds having isocyanate groups, and their use as components in the production of polyurethane plastics material | BAYER AG (DE) | 1982-03-17 | — | — | EP | claimed |
| EP-0000659-B1 | AN ISOCYANURATE COMPOSITION FORMED BY THE TRIMERISATION OF AN ISOCYANATE GROUP CONTAINING URETHANE OF AN AROMATIC POLYISOCYANATE AND A VINYLIDENECARBONYLOXYALKANOL AND SOLUTIONS, POLYMERS AND LAMINATES OBTAINED THEREFROM. | ICI AMERICAS INC. (US) | 1981-09-09 | — | — | EP | claimed |