Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1L1 | Q9UHC9 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | VDR | P11473 | 1/20 | 0.39 |
| ▸ | POLA1 | P09884 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11115189 | 1.00 | NPC1L1 (0.42) | NPC1L1MEN1USP2LMNATP53 | |
| SCHEMBL26669399 | 0.93 | GPBAR1 (0.47) | NPC1L1MEN1USP2LMNATP53 | |
| SCHEMBL9829186 | 0.93 | GPBAR1 (0.47) | NPC1L1MEN1USP2LMNATP53 | |
| SCHEMBL11116663 | 0.92 | NPC1L1 (0.41) | NPC1L1MEN1USP2LMNATP53 | |
| SCHEMBL11117436 | 0.92 | NPC1L1 (0.41) | NPC1L1MEN1USP2LMNATP53 | |
| SCHEMBL12136662 | 0.91 | POLB (0.46) | NPC1L1MEN1USP2LMNATP53 | |
| SCHEMBL22872155 | 0.91 | POLB (0.46) | NPC1L1MEN1USP2LMNATP53 | |
| SCHEMBL12138261 | 0.91 | POLB (0.46) | NPC1L1MEN1USP2LMNATP53 | |
| SCHEMBL9829516 | 0.89 | NPC1L1 (0.49) | NPC1L1MEN1USP2LMNATP53 | |
| SCHEMBL11778820 | 0.88 | NPC1L1 (0.48) | NPC1L1MEN1USP2LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4452793-A | INSECTICIDES | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1984-06-05 | — | — | US | disclosed |