Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.62 |
| ▸ | CA12 | O43570 | 2/20 | 0.62 |
| ▸ | CA1 | P00915 | 2/20 | 0.62 |
| ▸ | CA2 | P00918 | 2/20 | 0.62 |
| ▸ | CA7 | P43166 | 2/20 | 0.62 |
| ▸ | CA9 | Q16790 | 2/20 | 0.62 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | RARB | P10826 | 3/20 | 0.50 |
| ▸ | LTA4H | P09960 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10609795 | 1.00 | TSHR (0.62) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL10600260 | 1.00 | TSHR (0.62) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL7766693 | 1.00 | TSHR (0.62) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL10606881 | 1.00 | TSHR (0.62) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL10606406 | 1.00 | TSHR (0.62) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL10608025 | 1.00 | TSHR (0.62) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL10610971 | 1.00 | TSHR (0.62) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL3369946 | 1.00 | TSHR (0.62) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL10708683 | 1.00 | TSHR (0.62) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL7280610 | 1.00 | TSHR (0.62) | TSHRCA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250302839-A1 | COMPOSITIONS AND METHODS FOR DELIVERY OF RIBOFLAVIN | D&D Biopharmaceuticals, Inc. (US) | 2025-10-02 | — | — | US | disclosed |
| US-20110086802-A1 | METHODS TO INCREASE PERMEABILITY OF CORNEAL EPITHELIUM AND DESTABILIZE STROMAL COLLAGEN FIBRIL NETWORK | EUCLID SYSTEMS CORPORATION | 2011-04-14 | — | — | US | disclosed |
| EP-2278988-A2 | METHODS TO INCREASE PERMEABILITY OF CORNEAL EPITHELIUM AND DESTABILIZE STROMAL COLLAGEN FIBRIL NETWORK | Euclid Systems Corporation (US) | 2011-02-02 | — | — | EP | disclosed |
| WO-2009120549-A2 | METHODS TO INCREASE PERMEABILITY OF CORNEAL EPITHELIUM AND DESTABILIZE STROMAL COLLAGEN FIBRIL NETWORK | EUCLID SYSTEMS CORPORATION (US) | 2009-10-01 | — | — | WO | disclosed |
| EP-1051655-B1 | METHODS AND APPARATUS FOR ACCELERATED ORTHOKERATOLOGY | ISTA PHARMACEUTICALS INC (US) | 2005-09-28 | — | — | EP | disclosed |
| EP-1051655-A4 | METHODS AND APPARATUS FOR ACCELERATED ORTHOKERATOLOGY | ISTA PHARMACEUTICALS INC (US) | 2003-03-19 | — | — | EP | disclosed |
| US-20010016731-A1 | Methods and apparatus for accelerated orthokeratology | DEVORE DALE (US) | 2001-08-23 | — | — | US | disclosed |
| US-6161544-A | Methods for accelerated orthokeratology | KERATOFORM, INC. (US) | 2000-12-19 | — | — | US | disclosed |
| EP-1051655-A1 | METHODS AND APPARATUS FOR ACCELERATED ORTHOKERATOLOGY | Ista Pharmaceuticals, Inc. (US) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999039238-A1 | METHODS AND APPARATUS FOR ACCELERATED ORTHOKERATOLOGY | KERATOFORM, INC. (US) | 1999-08-05 | — | — | WO | disclosed |
| EP-0471894-B1 | Particulate toner material | AGFA GEVAERT NV (BE) | 1995-11-02 | — | — | EP | disclosed |
| US-5188919-A | Imparting negative charge with sulfonylanthranilic acid derivatives; thermoplastic resins as binder; developing latent electrostatic images; xerography | AGFA-GEVAERT, N.V. (BE) | 1993-02-23 | — | — | US | disclosed |
| EP-0471894-A1 | Particulate toner material | AGFA-GEVAERT N.V. (BE) | 1992-02-26 | — | — | EP | disclosed |
| US-4874894-A | Process for the production of benzenesulfonamides | HILTON DAVIS CO. (US) | 1989-10-17 | — | — | US | disclosed |