Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 18/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 18/20 | 0.39 |
| ▸ | PDE4A | P27815 | 3/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11116169 | 0.85 | PDE3B (0.45) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL11119202 | 0.84 | PDE3B (0.44) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL10754387 | 0.80 | PDE3B (0.44) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL10757648 | 0.75 | PDE3B (0.42) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL10377197 | 0.71 | PDE3B (0.45) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL10754103 | 0.70 | PDE3B (0.45) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL10755099 | 0.70 | PDE3B (0.46) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL10755971 | 0.68 | PDE3B (0.42) | PDE3BPDE3AP2RY12 | |
| SCHEMBL11116596 | 0.67 | PDE3B (0.57) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL11114939 | 0.66 | PDE3B (0.56) | PDE3BPDE3APDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0116948-A2 | (2-Oxo-1,2,3,5-tetrahydroimidazo-(2,1-b)quinazolinyl)-oxyalkyl-amides | SYNTEX (U.S.A.) INC. (US) | 1984-08-29 | — | — | EP | disclosed |