Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.51 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11118461 | 1.00 | AAK1 (0.51) | AAK1TBXAS1KMT2AMEN1NPC1 | |
| SCHEMBL15192091 | 0.89 | AAK1 (0.68) | AAK1TBXAS1KMT2AMEN1NPC1 | |
| SCHEMBL15192090 | 0.89 | AAK1 (0.68) | AAK1TBXAS1KMT2AMEN1NPC1 | |
| SCHEMBL14493754 | 0.87 | AAK1 (0.54) | AAK1KMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL5928301 | 0.84 | MEN1 (0.51) | AAK1TBXAS1KMT2AMEN1NPC1 | |
| SCHEMBL11130905 | 0.83 | AAK1 (0.51) | AAK1KMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL2566561 | 0.83 | AAK1 (0.51) | AAK1TBXAS1KMT2AMEN1NPC1 | |
| SCHEMBL28269146 | 0.82 | AAK1 (0.53) | AAK1TBXAS1KMT2AMEN1NPC1 | |
| SCHEMBL28269226 | 0.82 | AAK1 (0.74) | AAK1TBXAS1KMT2AMEN1NPC1 | |
| SCHEMBL1876173 | 0.82 | AAK1 (0.50) | AAK1KMT2AMEN1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57156453-A | — | — | None | — | — | JP | disclosed |
| EP-0047516-B1 | PROPYLAMINE DERIVATIVE AND PROCESS OF MANUFACTURING THE SAME | TORAY INDUSTRIES, INC. (JP) | 1984-01-04 | — | — | EP | disclosed |
| JP-S57156453-A | N-(DIPHENYLMETHYLENE)PROPYLAMINE DERIVATIVE | TORAY IND INC | 1982-09-27 | — | — | JP | disclosed |
| EP-0047516-A1 | Propylamine derivative and process of manufacturing the same | TORAY INDUSTRIES, INC. (JP) | 1982-03-17 | — | — | EP | disclosed |