Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MC4R | P32245 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10306180 | 0.81 | KMT2A (0.45) | KMT2AALDH1A1HPGDCYP2D6MAPK1 | |
| SCHEMBL10306179 | 0.81 | KMT2A (0.45) | KMT2AALDH1A1HPGDCYP2D6MAPK1 | |
| SCHEMBL6948451 | 0.80 | KMT2A (0.47) | KMT2AALDH1A1HPGDCYP2D6MAPK1 | |
| SCHEMBL6948453 | 0.80 | KMT2A (0.47) | KMT2AALDH1A1HPGDCYP2D6MAPK1 | |
| SCHEMBL6948454 | 0.80 | KMT2A (0.47) | KMT2AALDH1A1HPGDCYP2D6MAPK1 | |
| SCHEMBL12167713 | 0.79 | KMT2A (0.43) | KMT2AALDH1A1HPGDCYP2D6MAPK1 | |
| SCHEMBL12167674 | 0.79 | KMT2A (0.43) | KMT2AALDH1A1HPGDCYP2D6MAPK1 | |
| SCHEMBL4184392 | 0.77 | KMT2A (0.51) | KMT2AALDH1A1HPGDMAPK1HSD11B1 | |
| SCHEMBL3866850 | 0.76 | KMT2A (0.46) | KMT2AALDH1A1HPGDCYP2D6MAPK1 | |
| SCHEMBL17144597 | 0.76 | CYP2D6 (0.46) | KMT2AALDH1A1HPGDCYP2D6MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0114128-A1 | 3-Amino-2-oxo-azetidine derivatives containing in position 1 a nitrogen heterocyclic radical, process for their preparation, their use as therapeutical agents and intermediates for their preparation | ROUSSEL-UCLAF (FR) | 1984-07-25 | — | — | EP | disclosed |