Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 6/20 | 0.67 |
| ▸ | ESR1 | P03372 | 3/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.49 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CCR4 | P51679 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | PDE2A | O00408 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10790904 | 0.88 | HSD17B3 (0.68) | HSD17B3ESR1ESR2ERAP1CA2 | |
| SCHEMBL11113701 | 0.87 | HSD17B3 (0.67) | HSD17B3ESR1ESR2ERAP1CA2 | |
| SCHEMBL11119736 | 0.87 | HSD17B3 (0.67) | HSD17B3ESR1ESR2ERAP1CA2 | |
| SCHEMBL10846458 | 0.87 | HSD17B3 (0.70) | HSD17B3ESR1ESR2ERAP1CA2 | |
| SCHEMBL10790785 | 0.85 | HSD17B3 (0.63) | HSD17B3ESR1ESR2ERAP1CA2 | |
| SCHEMBL10794451 | 0.85 | MAOB (0.65) | HSD17B3HPGDMAOB | |
| SCHEMBL11117198 | 0.85 | HSD17B3 (0.63) | HSD17B3ESR1ESR2ERAP1CA2 | |
| SCHEMBL10791803 | 0.84 | HSD17B3 (0.62) | HSD17B3ESR1ESR2ERAP1CA2 | |
| SCHEMBL10791341 | 0.84 | HSD17B3 (0.62) | HSD17B3ESR1ESR2ERAP1CA2 | |
| SCHEMBL10847031 | 0.83 | HSD17B3 (0.84) | HSD17B3ESR1ESR2ERAP1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0111746-A2 | Sulfonic-acid esters of hydroxycoumarines, their preparation and medicines containing them | BASF Aktiengesellschaft (DE) | 1984-06-27 | — | — | EP | disclosed |