Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.39 |
| ▸ | ESR1 | P03372 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9863302 | 0.91 | TSHR (0.41) | TSHRTDP1L3MBTL1CHRM2CHRM4 | |
| SCHEMBL9863146 | 0.79 | TSHR (0.46) | TSHRTDP1L3MBTL1CHRM2CHRM4 | |
| SCHEMBL234625 | 0.78 | TSHR (0.52) | TSHRTDP1L3MBTL1CHRM2CHRM4 | |
| SCHEMBL9862999 | 0.77 | TSHR (0.46) | TSHRCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL4449462 | 0.75 | TSHR (0.49) | TSHRTDP1L3MBTL1CHRM2CHRM4 | |
| SCHEMBL11564363 | 0.74 | TSHR (0.55) | TSHRTDP1L3MBTL1CHRM2CHRM4 | |
| SCHEMBL28077230 | 0.73 | TSHR (0.49) | TSHRCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL8975464 | 0.72 | TSHR (0.54) | TSHRCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL16732318 | 0.72 | TSHR (0.54) | TSHRCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9863046 | 0.72 | TSHR (0.54) | TSHRCHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0115195-A1 | Catalyst composition for use in the polymerization of olefins | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1984-08-08 | — | — | EP | disclosed |