Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 3/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11115783 | 1.00 | PTGIR (0.54) | PTGIRPDE4BTSHRHPGDTP53 | |
| SCHEMBL11116578 | 1.00 | PTGIR (0.54) | PTGIRPDE4BTSHRHPGDTP53 | |
| SCHEMBL11946690 | 0.99 | PTGIR (0.55) | PTGIRPDE4BTSHRHPGDTP53 | |
| Clanobutin SCHEMBL5055263 | 0.95 | PTGIR (0.56) | PTGIRPDE4BTSHRHPGDTP53 | |
| Clanobutin SCHEMBL667903 | 0.95 | PTGIR (0.56) | PTGIRPDE4BTSHRHPGDTP53 | |
| Clanobutin SCHEMBL3850118 | 0.94 | PTGIR (0.55) | PTGIRPDE4BTSHRHPGDTP53 | |
| SCHEMBL11117217 | 0.94 | PDE4B (0.55) | PTGIRPDE4BTSHRHPGDTP53 | |
| SCHEMBL11232801 | 0.93 | PTGIR (0.50) | PTGIRPDE4BTSHRHPGDTP53 | |
| SCHEMBL11314317 | 0.91 | PTGIR (0.52) | PTGIRPDE4BTSHRHPGDTP53 | |
| SCHEMBL11217740 | 0.90 | PTGIR (0.53) | PTGIRPDE4BTSHRHPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0051828-B1 | N-BENZOYL-ALPHA-ANILINO ALKANE CARBOXYLIC ACIDS, SALTS AND ESTERS THEREOF, PROCESS FOR PRODUCING THE SAME AND PHARMACEUTICAL PREPARATIONS CONTAINING THE SAME | A. Nattermann & Cie. GmbH (DE) | 1984-03-14 | — | — | EP | claimed |
| EP-0051828-B1 | N-BENZOYL-ALPHA-ANILINO ALKANE CARBOXYLIC ACIDS, SALTS AND ESTERS THEREOF, PROCESS FOR PRODUCING THE SAME AND PHARMACEUTICAL PREPARATIONS CONTAINING THE SAME | A. Nattermann & Cie. GmbH (DE) | 1984-03-14 | — | — | EP | disclosed |
| US-4386031-A | ANTICOAGULANTS; ANTIALLERGENS; ANTINFLAM-MATORY AND ANTILIPEMIC AGENTS; ANTIHISTAMINES; CARDIOVASCULAR DISORDERS | A. NATTERMANN & CIE GMBH (DE) | 1983-05-31 | — | — | US | disclosed |
| EP-0051828-A1 | N-benzoyl-alpha-anilino alkane carboxylic acids, salts and esters thereof, process for producing the same and pharmaceutical preparations containing the same | A. Nattermann & Cie. GmbH (DE) | 1982-05-19 | — | — | EP | disclosed |