SCHEMBL11117587

SCHEMBL11117587

CCCCCc1ccc2oc3ccccc3c(=S)c2c1

nearest known ligand 0.55

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.55
CYP2D6 P10635 1/20 0.55
CYP2C19 P33261 1/20 0.55
RORA P35398 1/20 0.42
RORC P51449 1/20 0.42
RORB Q92753 1/20 0.42
PDE10A Q9Y233 2/20 0.42
GPR3 P46089 1/20 0.40
PTPN1 P18031 2/20 0.39
MAPT P10636 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9499548 0.99 CYP1A2 (0.54) CYP1A2CYP2D6CYP2C19RORARORC
SCHEMBL11119825 0.99 CYP1A2 (0.54) CYP1A2CYP2D6CYP2C19RORARORC
SCHEMBL1823418 0.99 CYP1A2 (0.54) CYP1A2CYP2D6CYP2C19RORARORC
SCHEMBL11120439 0.96 CYP1A2 (0.56) CYP1A2CYP2D6CYP2C19PDE10APTPN1
SCHEMBL7783535 0.90 CYP1A2 (0.51) CYP1A2CYP2D6CYP2C19PDE10APTPN1
SCHEMBL16806183 0.85 CYP1A2 (0.66) CYP1A2CYP2D6CYP2C19RORARORC
SCHEMBL248557 0.83 CYP1A2 (0.46) CYP1A2CYP2D6CYP2C19PDE10AMAPT
SCHEMBL5337478 0.83 CYP1A2 (0.56) CYP1A2CYP2D6CYP2C19
SCHEMBL8642862 0.82 CYP1A2 (0.54) CYP1A2CYP2D6CYP2C19RORARORC
SCHEMBL5312146 0.82 CYP1A2 (0.54) CYP1A2CYP2D6CYP2C19RORARORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0036075-B1 MIXTURES BASED ON AROMATIC-ALIPHATIC KETONES, THEIR USE AS PHOTOINITIATORS AND PHOTOPOLYMERISABLE SYSTEMS CONTAINING SUCH MIXTURES MERCK PATENT GmbH (DE) 1984-06-06 EP disclosed
EP-0036075-A1 Mixtures based on aromatic-aliphatic ketones, their use as photoinitiators and photopolymerisable systems containing such mixtures MERCK PATENT GmbH (DE) 1981-09-23 EP disclosed