Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.67 |
| ▸ | GALR3 | O60755 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11245223 | 0.86 | HPGD (0.80) | MAPTSMN1; SMN2GALR3CYP3A4CYP2C9 | |
| SCHEMBL7265939 | 0.85 | SMN1; SMN2 (0.72) | MAPTSMN1; SMN2GALR3CYP3A4CYP2C9 | |
| SCHEMBL10668976 | 0.84 | MAPT (0.67) | MAPTSMN1; SMN2GALR3CYP3A4CYP2C9 | |
| SCHEMBL9475498 | 0.84 | NPC1 (0.59) | MAPTSMN1; SMN2GALR3CYP3A4CYP2C9 | |
| SCHEMBL10348470 | 0.83 | SMN1; SMN2 (0.67) | MAPTSMN1; SMN2GALR3CYP3A4CYP2C9 | |
| SCHEMBL10419778 | 0.83 | HPGD (0.55) | MAPTSMN1; SMN2GALR3CYP3A4CYP2C9 | |
| SCHEMBL9477980 | 0.81 | SMN1; SMN2 (0.66) | MAPTSMN1; SMN2GALR3CYP3A4CYP2C9 | |
| SCHEMBL10348660 | 0.80 | SMN1; SMN2 (0.70) | MAPTSMN1; SMN2GALR3CYP3A4CYP2C9 | |
| SCHEMBL10666069 | 0.80 | SMN1; SMN2 (0.56) | MAPTSMN1; SMN2GALR3CYP3A4CYP2C9 | |
| SCHEMBL16179036 | 0.79 | HSD17B10 (0.58) | MAPTSMN1; SMN2GALR3CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0114347-A2 | Aralkyl-triazole compounds | CIBA-GEIGY AG (CH) | 1984-08-01 | — | — | EP | claimed |
| EP-0114347-A2 | Aralkyl-triazole compounds | CIBA-GEIGY AG (CH) | 1984-08-01 | — | — | EP | disclosed |