Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12376675 | 0.84 | HDAC2 (0.61) | HDAC2HDAC8HDAC6HDAC1MAPT | |
| SCHEMBL15143002 | 0.81 | HDAC2 (0.53) | HDAC2HDAC8HDAC6HDAC1MAPT | |
| SCHEMBL11114265 | 0.80 | HDAC2 (0.51) | HDAC2HDAC8HDAC6HDAC1MAPT | |
| SCHEMBL11119117 | 0.79 | HDAC2 (0.54) | HDAC2HDAC8HDAC6HDAC1MAPT | |
| SCHEMBL21758222 | 0.78 | HDAC2 (0.58) | HDAC2HDAC8HDAC6HDAC1MAPT | |
| SCHEMBL4778260 | 0.77 | HDAC2 (0.61) | HDAC2HDAC8HDAC6HDAC1MAPT | |
| SCHEMBL28250846 | 0.77 | HDAC2 (0.56) | HDAC2HDAC8HDAC6HDAC1MAPT | |
| SCHEMBL16290162 | 0.76 | GAA (0.50) | HDAC2HDAC8HDAC6HDAC1MAPT | |
| Hydrochloric Acid SCHEMBL6557840 | 0.76 | HDAC2 (0.59) | HDAC2HDAC8HDAC6HDAC1MAPT | |
| SCHEMBL5654470 | 0.75 | HDAC2 (0.50) | HDAC2HDAC8HDAC6HDAC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0035743-B1 | PROCESS FOR THE PREPARATION OF DIPEPTIDES | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1984-11-07 | — | — | EP | disclosed |
| US-4352752-A | Process for the preparation of dipeptides | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1982-10-05 | — | — | US | disclosed |
| EP-0035743-A1 | Process for the preparation of dipeptides | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1981-09-16 | — | — | EP | disclosed |