Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 19/20 | 0.78 |
| ▸ | BCL2L1 | Q07817 | 18/20 | 0.78 |
| ▸ | BCL2L2 | Q92843 | 3/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1111803 | 1.00 | BCL2 (0.78) | BCL2BCL2L1BCL2L2 | |
| SCHEMBL1677422 | 0.95 | BCL2 (0.85) | BCL2BCL2L1BCL2L2 | |
| SCHEMBL1677421 | 0.95 | BCL2 (0.85) | BCL2BCL2L1BCL2L2 | |
| Methyl Alcohol SCHEMBL1113152 | 0.94 | BCL2 (0.83) | BCL2BCL2L1BCL2L2 | |
| SCHEMBL1111745 | 0.92 | BCL2 (0.90) | BCL2BCL2L1BCL2L2 | |
| SCHEMBL1111748 | 0.92 | BCL2 (0.90) | BCL2BCL2L1BCL2L2 | |
| SCHEMBL1112405 | 0.92 | BCL2 (0.90) | BCL2BCL2L1BCL2L2 | |
| SCHEMBL1111952 | 0.91 | BCL2 (0.79) | BCL2BCL2L1BCL2L2 | |
| SCHEMBL1111956 | 0.91 | BCL2 (0.79) | BCL2BCL2L1BCL2L2 | |
| SCHEMBL1111855 | 0.90 | BCL2 (0.85) | BCL2BCL2L1BCL2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2279174-A2 | ARYLSULFONAMIDE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | Genentech, Inc. (US) | 2011-02-02 | — | — | EP | disclosed |
| WO-2009143246-A2 | ARYLSULFONAMIDE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | GENENTECH, INC. (US) | 2009-11-26 | — | — | WO | disclosed |