Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 3/20 | 0.86 |
| ▸ | NR3C2 | P08235 | 5/20 | 0.68 |
| ▸ | PGR | P06401 | 5/20 | 0.67 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.67 |
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.67 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | MLNR | O43193 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.67 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11118072 | 1.00 | AR (0.86) | ARNR3C2PGRNR3C1CYP3A4 | |
| SCHEMBL11229308 | 0.94 | AR (0.89) | ARNR3C2PGRNR3C1CYP3A4 | |
| SCHEMBL11020429 | 0.94 | AR (0.89) | ARNR3C2PGRNR3C1CYP3A4 | |
| Clascoterone SCHEMBL24358737 | 0.92 | AR (1.00) | ARNR3C2PGRNR3C1CYP3A4 | |
| Clascoterone SCHEMBL25297448 | 0.92 | AR (1.00) | ARNR3C2PGRNR3C1CYP3A4 | |
| Clascoterone SCHEMBL24688164 | 0.92 | AR (1.00) | ARNR3C2PGRNR3C1CYP3A4 | |
| SCHEMBL10937146 | 0.92 | AR (0.86) | ARNR3C2PGRNR3C1CYP3A4 | |
| Clascoterone SCHEMBL24688449 | 0.92 | AR (1.00) | ARNR3C2PGRNR3C1CYP3A4 | |
| Clascoterone SCHEMBL24687898 | 0.92 | AR (1.00) | ARNR3C2PGRNR3C1CYP3A4 | |
| Clascoterone SCHEMBL1231152 | 0.92 | AR (1.00) | ARNR3C2PGRNR3C1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4440689-A | Acyloxysteroids and process for producing same | MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) | 1984-04-03 | — | — | US | disclosed |
| EP-0071178-A1 | Acyloxysteroids and process for producing same | MITSUBISHI KASEI CORPORATION (JP) | 1983-02-09 | — | — | EP | disclosed |