Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.33 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11123116 | 0.93 | CSNK2A2 (0.33) | HDAC3HDAC1HDAC2SMARCA2SMARCA4 | |
| SCHEMBL11121478 | 0.90 | SMARCA2 (0.34) | SMARCA2SMARCA4 | |
| SCHEMBL11122319 | 0.90 | HDAC3 (0.40) | HDAC3HDAC1HDAC2SMARCA2SMARCA4 | |
| SCHEMBL11115792 | 0.84 | SMARCA2 (0.34) | SMARCA2SMARCA4MAPT | |
| SCHEMBL11117809 | 0.83 | NPY5R (0.42) | SMARCA2SMARCA4 | |
| SCHEMBL11127363 | 0.83 | ABCC1 (0.40) | SMARCA2SMARCA4 | |
| SCHEMBL11118646 | 0.82 | MEN1 (0.37) | SMARCA2SMARCA4MAPT | |
| SCHEMBL11122300 | 0.81 | SMARCA2 (0.34) | SMARCA2SMARCA4MAPT | |
| SCHEMBL11123858 | 0.81 | HDAC3 (0.37) | HDAC3HDAC1HDAC2MAPT | |
| SCHEMBL11118756 | 0.79 | SMARCA2 (0.33) | SMARCA2SMARCA4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0129408-A2 | (3-alkyl-5-isothiazolyl)ureas | ELI LILLY AND COMPANY (US) | 1984-12-27 | — | — | EP | disclosed |