Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9317312 | 0.84 | TDP1 (0.43) | TDP1MAPTMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL11152658 | 0.80 | TDP1 (0.41) | TDP1MAPTMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL11217086 | 0.80 | TDP1 (0.41) | TDP1MAPTMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL11152660 | 0.80 | TDP1 (0.41) | TDP1MAPTMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL7660650 | 0.77 | TDP1 (0.39) | TDP1MAPTMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL7660645 | 0.77 | TDP1 (0.39) | TDP1MAPTMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL9765865 | 0.72 | TDP1 (0.46) | TDP1MAPTMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL11120044 | 0.71 | TDP1 (0.36) | TDP1MAPTMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL11120046 | 0.71 | TDP1 (0.36) | TDP1MAPTMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL11696161 | 0.70 | MAPT (0.57) | TDP1MAPTMAPK1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0123996-A1 | N-cyclohexadienyl-chloracetamides | BAYER AG (DE) | 1984-11-07 | — | — | EP | disclosed |