Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 15/20 | 0.82 |
| ▸ | ACE2 | Q9BYF1 | 7/20 | 0.82 |
| ▸ | LTA4H | P09960 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11120692 | 1.00 | ACE (0.82) | ACEACE2LTA4H | |
| SCHEMBL11121217 | 0.90 | ACE (0.79) | ACEACE2LTA4H | |
| SCHEMBL11122708 | 0.90 | ACE (1.00) | ACEACE2 | |
| SCHEMBL11122713 | 0.90 | ACE (1.00) | ACEACE2 | |
| SCHEMBL6442128 | 0.88 | ACE (0.74) | ACEACE2LTA4H | |
| SCHEMBL6442125 | 0.88 | ACE (0.74) | ACEACE2LTA4H | |
| SCHEMBL11122051 | 0.88 | ACE (0.65) | ACEACE2 | |
| SCHEMBL11122057 | 0.88 | ACE (0.65) | ACEACE2 | |
| SCHEMBL11124339 | 0.88 | ACE (0.81) | ACEACE2 | |
| SCHEMBL11279585 | 0.88 | ACE (0.81) | ACEACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0045161-B1 | AMIDES OF 4-OXO-5-AMIDOHEXANOIC ACID DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-03-14 | — | — | EP | claimed |
| EP-0045161-A1 | Amides of 4-oxo-5-amidohexanoic acid derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-02-03 | — | — | EP | claimed |
| EP-0045161-B1 | AMIDES OF 4-OXO-5-AMIDOHEXANOIC ACID DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-03-14 | — | — | EP | disclosed |
| EP-0045161-A1 | Amides of 4-oxo-5-amidohexanoic acid derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-02-03 | — | — | EP | disclosed |