Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 13/20 | 0.61 |
| ▸ | BCL2L1 | Q07817 | 9/20 | 0.61 |
| ▸ | BCL2L2 | Q92843 | 4/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1112294 | 1.00 | BCL2 (0.61) | BCL2BCL2L1BCL2L2 | |
| SCHEMBL1677439 | 0.94 | BCL2 (0.69) | BCL2BCL2L1BCL2L2 | |
| SCHEMBL1677440 | 0.94 | BCL2 (0.69) | BCL2BCL2L1BCL2L2 | |
| SCHEMBL1113858 | 0.85 | BCL2L1 (0.66) | BCL2BCL2L1BCL2L2 | |
| SCHEMBL1677546 | 0.84 | BCL2 (0.61) | BCL2BCL2L1BCL2L2 | |
| SCHEMBL1112506 | 0.84 | BCL2 (0.74) | BCL2BCL2L1BCL2L2 | |
| SCHEMBL1112503 | 0.84 | BCL2 (0.74) | BCL2BCL2L1BCL2L2 | |
| SCHEMBL1112071 | 0.83 | BCL2 (0.74) | BCL2BCL2L1BCL2L2 | |
| SCHEMBL1112066 | 0.83 | BCL2 (0.74) | BCL2BCL2L1BCL2L2 | |
| SCHEMBL1113183 | 0.83 | BCL2 (0.78) | BCL2BCL2L1BCL2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2279174-A2 | ARYLSULFONAMIDE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | Genentech, Inc. (US) | 2011-02-02 | — | — | EP | disclosed |
| WO-2009143246-A2 | ARYLSULFONAMIDE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | GENENTECH, INC. (US) | 2009-11-26 | — | — | WO | disclosed |